Genome wide association study and differential gene expression of Drosophila melanogaster under heat and cold stress

1 MA plots

All MA plots now have an FDR of 0.01 and no fold-change cutoff.

1.1 No gene labels

Cold v Ctrl MA plot

Hot v Ctrl MA plot

1.2 Labeled by padj

Cold v Ctrl MA plot

Hot v Ctrl MA plot

1.3 GWAS points

Cold v Ctrl MA plot

Hot v Ctrl MA plot

1.4 GWAS labels

Cold v Ctrl MA plot

Hot v Ctrl MA plot

1.5 GWAS labels colored by DEG sig

Cold v Ctrl MA plot

Hot v Ctrl MA plot

2 Expression Venn Diagrams

2.1 Up-regulated genes

2.2 Down-regulated genes

3 Top 50 differentially expressed genes

Download full DESeq2 gene expression results

3.1 Heat shock

gene	hot_fc	log2FoldChange.hot	padj.hot
CG3339	down	-5.155	1.097e-27
l(2)08717	down	-2.3	4.051e-25
pip	down	-3.434	5.188e-24
stan	down	-2.592	2.063e-23
Dhc36C	down	-2.724	1.51e-22
ft	down	-3.361	4.602e-22
CG17075	down	-2.455	5.379e-22
CG1801	down	-3.692	2.458e-21
CG9492	down	-4.122	2.881e-20
Dhc93AB	down	-3.104	1.029e-19
Dscam1	down	-1.795	1.792e-19
CG42534	down	-4.148	4.16e-19
CG6125	down	-2.153	7.197e-19
CG1688	down	-3.061	8.789e-19
btv	down	-4.624	1.002e-18
Sb	down	-4.59	1.126e-18
CG43980	down	-4.82	1.34e-18
Muc14A	down	-2.612	1.372e-18
hiw	down	-1.521	1.414e-18
CG3348	down	-3.219	1.822e-18
Nos	down	-3.834	2.877e-18
CG30263	down	-3.978	4.212e-18
jv	down	-2.334	4.212e-18
conv	down	-4.136	4.94e-18
NT1	down	-6.652	4.94e-18
Dop1R1	down	-2.643	6.474e-18
Shawl	down	-3.459	8.688e-18
CG8745	down	-2.145	1.314e-17
CG14304	down	-4.486	1.542e-17
CG31465	down	-6.373	2.078e-17
Ugt86Di	down	-5.074	4.038e-17
CR44327	down	-2.536	4.654e-17
salr	down	-3.028	4.671e-17
nompC	down	-3.89	6.068e-17
SIFaR	down	-4.022	6.357e-17
Nlg4	down	-2.488	8.891e-17
CG15894	down	-2.427	1.946e-16
Cda5	down	-1.12	2.097e-16
CG4744	down	-6.327	2.705e-16
eag	down	-1.729	2.931e-16
CG30272	down	-3.39	3.009e-16
Ac78C	down	-2.352	3.672e-16
CG45105	down	-3.336	4.007e-16
Rab26	down	-2.214	4.049e-16
CG12950	down	-2.918	4.628e-16
CG32791	down	-1.702	5.419e-16
TkR99D	down	-3.825	8.6e-16
Ddr	down	-3.329	9.219e-16
GABA-B-R1	down	-2.256	1.09e-15
Sytbeta	down	-3.292	1.449e-15
Hsp68	up	6.888	0
DnaJ-1	up	3.727	2.219e-143
Hsp70Bb	up	7.003	2.219e-143
stv	up	4.471	2.373e-104
Hsp26	up	4.279	5.676e-72
Hsp67Bc	up	4.785	2.957e-71
Hsp27	up	3.532	4.06e-62
Hsp83	up	2.106	6.281e-58
Hsp23	up	6.872	8.789e-53
Nop17l	up	1.614	7.563e-52
CG6770	up	1.78	5.402e-48
Hop	up	1.305	1.268e-43
CG42240	up	1.131	1.65e-41
Hsc70Cb	up	1.271	5.313e-38
Jafrac1	up	0.8308	7.251e-38
CG16721	up	1.484	1.699e-36
CG1416	up	1.24	1.833e-34
CG5290	up	1.882	8.359e-34
Droj2	up	1.165	9.102e-33
Hsc70-3	up	1.522	2.984e-32
Lsd-2	up	1.004	2.845e-30
alphagamma-element:CR32865	up	6.317	1.507e-29
sra	up	1.258	9.836e-29
CG10600	up	1.189	1.267e-28
Mlf	up	1.019	1.689e-28
Capr	up	0.9256	6.875e-28
mim	up	1.18	1.125e-26
Hsp70Bc	up	5.778	5.299e-26
CG10077	up	1.398	5.714e-26
Pgi	up	0.9688	3e-25
ref(2)P	up	1.398	7.851e-24
CG7033	up	1.009	4.144e-23
e(y)3	up	0.9014	8.199e-23
Trxr-1	up	1.139	1.335e-22
Pa1	up	1.987	1.445e-22
CG1943	up	1.14	1.445e-22
PEK	up	1.254	5.637e-22
GstD1	up	0.8593	7.088e-22
phol	up	1.028	8.707e-22
CG3680	up	0.8435	4.633e-21
TfIIEalpha	up	1.076	1.121e-20
da	up	0.8578	2.725e-20
cact	up	0.8173	3.294e-20
Ran	up	0.7748	6.905e-20
CG1677	up	0.8251	9.427e-20
betaTub56D	up	1.038	1.749e-19
Cctgamma	up	0.8277	6.345e-19
BRWD3	up	0.8852	7.197e-19
l(1)G0469	up	1.272	7.197e-19
Pdk	up	1.35	1.224e-18

3.2 Cold shock

gene	cold_fc	log2FoldChange.cold	padj.cold
stan	down	-2.535	2.296e-20
Dhc93AB	down	-3.204	2.253e-19
CG3339	down	-4.294	5.99e-19
CG1801	down	-3.666	5.99e-19
CG3280	down	-3.068	5.99e-19
CG42534	down	-4.469	7.335e-19
CG32791	down	-1.855	1.687e-17
ft	down	-2.987	8.646e-17
pip	down	-2.89	1.435e-16
Dscam1	down	-1.683	2.136e-16
CG43163	down	-3.52	4.912e-16
CG9492	down	-3.725	5.06e-16
rk	down	-3.238	8.245e-16
Dhc36C	down	-2.296	1.463e-15
CG8219	down	-5.491	1.463e-15
SIFaR	down	-4.039	2.331e-15
Ac78C	down	-2.361	3.608e-15
Ddr	down	-3.388	6.724e-15
d	down	-3.775	1.027e-14
CR45604	down	-3.018	1.027e-14
mtt	down	-3.664	1.135e-14
Dhc62B	down	-3.892	1.49e-14
iav	down	-4.075	1.696e-14
CR45272	down	-4.647	2.839e-14
prom	down	-2.737	2.839e-14
CG18519	down	-3.233	2.839e-14
CG43110	down	-3.216	4.113e-14
Nep5	down	-3.804	4.113e-14
conv	down	-3.69	6.626e-14
rdgC	down	-1.94	6.946e-14
Shawl	down	-3.097	7.672e-14
CG44153	down	-3.691	8.047e-14
Hsp68	down	-1.071	8.344e-14
GluRIB	down	-2.415	9.254e-14
CG45002	down	-1.938	9.254e-14
Sb	down	-3.89	1.557e-13
Nlg4	down	-2.28	1.557e-13
CG4744	down	-5.989	1.789e-13
trh	down	-2.138	2.011e-13
btv	down	-3.901	2.345e-13
rdo	down	-3.167	2.827e-13
Dop1R1	down	-2.284	4.304e-13
unc-13-4A	down	-2.109	4.464e-13
TrpA1	down	-4.111	4.79e-13
CG42255	down	-1.631	5.093e-13
CG31814	down	-3.185	5.781e-13
rad	down	-1.922	6.059e-13
Muc68Ca	down	-3.064	6.059e-13
CG43795	down	-2.427	6.591e-13
eag	down	-1.562	7.105e-13
Jafrac1	up	0.6228	1.102e-19
Lsd-2	up	0.8045	1.486e-18
endos	up	0.7605	1.544e-17
D1	up	0.684	1.687e-17
Muc4B	up	2.542	1.687e-17
Capr	up	0.7236	2.497e-16
CG14478	up	0.8465	3.717e-15
CG1677	up	0.73	7.404e-15
Ran	up	0.6814	7.51e-15
CG15771	up	0.6845	1.537e-14
bif	up	0.7919	2.869e-14
GstD1	up	0.7024	3.842e-14
e(y)3	up	0.7182	4.174e-14
mts	up	0.638	6.428e-14
phol	up	0.8291	9.254e-14
east	up	0.7952	1.511e-13
Act5C	up	0.6184	2.345e-13
CG8223	up	0.9441	2.752e-13
cact	up	0.6657	4.446e-13
Rip11	up	0.7142	5.651e-13
CG1440	up	0.6414	5.951e-13
ssx	up	0.6681	7.105e-13
swa	up	0.8273	1.017e-12
tral	up	0.8757	1.203e-12
CG1943	up	0.8542	1.883e-12
Pen	up	0.898	2.887e-12
cib	up	0.8765	3.891e-12
nocte	up	0.7272	5.576e-12
CG6597	up	0.6554	5.593e-12
CG8963	up	0.6505	5.707e-12
mim	up	0.7948	6.11e-12
Hmt4-20	up	0.7751	6.589e-12
CG12262	up	0.8364	1.29e-11
26-29-p	up	0.8999	1.457e-11
rngo	up	0.6756	1.476e-11
Jupiter	up	0.6516	1.526e-11
CG4511	up	0.7374	1.68e-11
da	up	0.6498	1.814e-11
pr-set7	up	0.8255	2.345e-11
Cap	up	0.775	2.683e-11
CG10492	up	0.844	2.975e-11
Gapdh2	up	0.7177	3.343e-11
Rpt1	up	0.5432	3.942e-11
Df31	up	0.7823	4.048e-11
CG8108	up	0.6396	4.688e-11
betaTub56D	up	0.7807	5.6e-11
Upf1	up	0.6236	5.655e-11
CG9705	up	0.7375	8.723e-11
Abi	up	0.6488	8.733e-11
Amun	up	0.7009	9.284e-11

4 DEG LFC scatter & GWAS Density

4.1 GWAS scatter & density plots (10^-5)

K.S. pairwise comparisons of the distributions of top GWAS genes under shock

GWAS distributions	Heat-shock	Cold-shock
Other vs. CTmin	0.5641033	0.5775028
Other vs. CTmax	0.4426838	0.6970872
CTmin vs. CTmax	0.5715501	0.8135801

4.2 GWAS scatter & density plots (10^-4)

K.S. pairwise comparisons of the distributions of top GWAS genes under shock

GWAS distributions	Heat-shock	Cold-shock
Other vs. CTmin	0.1562769	0.0624962
Other vs. CTmax	0.0063858	0.0102758
CTmin vs. CTmax	0.1697556	0.0511528

4.3 GWAS scatter with relevant density plot

5 GWAS (pval cutoff 10^-5)

5.1 Summary

GWAS	SNPs	SNPs annotated to genes	Unique genes	Sig DEGs	NS DEGs	No RNAseq data
CTmax	21	19	12	9	3	0
CTmin	53	50	26	11	12	3
ThermalBreadth	23	19	17	NA	NA	17

5.2 Venn Diagram: SNPs & Genes

1. The top GWAS SNPs (10^-5) associated with each phenotype. B. The unique genes associated with those top SNPs

5.2.1 Without thermal breadth

1. The top GWAS SNPs (10^-5) associated with each phenotype. B. The unique genes associated with those top SNPs

5.3 CTmax

5.3.1 All hits

ID	gene	grps	AvgMixedPval
2R_10330800_INS	Oaz	INTRON	8.0e-07
2R_6398772_SNP	lola	INTRON	9.0e-07
2R_6398743_SNP	lola	INTRON	9.0e-07
2R_10330805_SNP	Oaz	INTRON	1.0e-06
3R_22515826_SNP			2.3e-06
2L_12384183_SNP	bru-2	INTRON	2.4e-06
3R_25373467_SNP			2.5e-06
2R_17564376_SNP	CG30263	SYNONYMOUS_CODING	2.6e-06
2R_10330722_SNP	Oaz	INTRON	3.0e-06
X_3381582_SNP	CR44999	INTRON	3.2e-06
X_3381582_SNP	CG10803	INTRON	3.2e-06
X_3381590_SNP	CG10803	INTRON	3.2e-06
X_3381590_SNP	CR44999	INTRON	3.2e-06
2R_10330717_SNP	Oaz	INTRON	3.5e-06
X_3381391_SNP	CR44999	INTRON	3.7e-06
X_3381391_SNP	CG10803	INTRON	3.7e-06
X_3381587_SNP	CR44999	INTRON	4.1e-06
X_3381587_SNP	CG10803	INTRON	4.1e-06
3L_9575326_SNP	CG42673	INTRON	6.0e-06
X_5876026_SNP	Grip	INTRON	6.0e-06
3R_3427376_SNP	CG34127	INTRON	7.6e-06
2L_19428598_SNP	CG13085	INTRON	8.4e-06
2L_19428598_SNP	CG16771	INTRON	8.4e-06
2R_10330701_SNP	Oaz	INTRON	9.7e-06
2L_19428336_SNP	CG13085	INTRON	9.9e-06
2L_19428336_SNP	CG16771	INTRON	9.9e-06
3R_20025347_SNP	twin	INTRON	1.0e-05

5.3.2 Group count

grps	n
INTRON	24
SYNONYMOUS_CODING	1

5.3.3 Gene counts

gene	n
Oaz	5
CG10803	4
CR44999	4
CG13085	2
CG16771	2
lola	2
bru-2	1
CG30263	1
CG34127	1
CG42673	1
Grip	1
twin	1

5.4 CTmin

5.4.1 All hits

ID	gene	grps	AvgMixedPval
2R_20313579_SNP	prom	INTRON	0.0e+00
2R_20313579_SNP	CG42383	INTRON	0.0e+00
X_4385442_SNP	CR32773	INTRON	1.0e-07
3R_13900959_SNP			2.0e-07
2R_20308502_SNP	prom	INTRON	4.0e-07
3R_12992895_SNP	Mur89F	INTRON	7.0e-07
2R_20313917_SNP	prom	INTRON	9.0e-07
2R_20313922_DEL	prom	INTRON	9.0e-07
2R_20313930_SNP	prom	INTRON	9.0e-07
2R_20313933_SNP	prom	INTRON	9.0e-07
2R_20313935_INS	prom	INTRON	9.0e-07
2R_20313938_SNP	prom	INTRON	9.0e-07
2R_20313940_MNP	prom	INTRON	9.0e-07
2R_20308558_SNP	prom	INTRON	1.0e-06
2R_20250118_SNP	bs	INTRON	1.0e-06
2R_20250118_SNP	CR44811	INTRON	1.0e-06
2R_20301097_SNP	CG45068	SYNONYMOUS_CODING	1.1e-06
2R_20301097_SNP	CG45069	SYNONYMOUS_CODING	1.1e-06
2R_20301239_SNP	CG45068	NON_SYNONYMOUS_CODING	1.1e-06
2R_20301239_SNP	CG45069	NON_SYNONYMOUS_CODING	1.1e-06
2R_20308533_SNP	prom	INTRON	1.2e-06
2R_20313914_SNP	prom	INTRON	1.3e-06
2L_2612712_SNP			1.4e-06
2R_20313927_SNP	prom	INTRON	1.5e-06
2R_20313911_SNP	prom	INTRON	1.8e-06
2R_20307893_SNP	prom	NON_SYNONYMOUS_CODING	1.8e-06
2R_20313916_SNP	prom	INTRON	1.9e-06
2R_20308565_SNP	prom	INTRON	1.9e-06
2R_20309964_SNP	prom	INTRON	2.0e-06
2R_20309106_SNP	prom	INTRON	2.2e-06
3R_11364111_SNP	CG18519	SYNONYMOUS_CODING	2.2e-06
2R_20313919_SNP	prom	INTRON	2.4e-06
3R_14850882_SNP	CG14285	NON_SYNONYMOUS_CODING	3.1e-06
3R_14850882_SNP	CG14286	NON_SYNONYMOUS_CODING	3.1e-06
2R_20313912_SNP	prom	INTRON	3.2e-06
2L_3465546_SNP	msl-2	NON_SYNONYMOUS_CODING	3.2e-06
2L_3465546_SNP	Pdsw	NON_SYNONYMOUS_CODING	3.2e-06
2R_20301123_SNP	CG45069	UTR_5_PRIME	3.3e-06
2R_20301123_SNP	CG45068	UTR_5_PRIME	3.3e-06
3R_13552400_SNP	Lgr1	INTRON	3.6e-06
3R_11367299_SNP	CG18519	NON_SYNONYMOUS_CODING	4.0e-06
3R_11288771_SNP	AdamTS-A	INTRON	4.2e-06
2R_20301091_SNP	CG45069	UTR_5_PRIME	4.2e-06
2R_20301091_SNP	CG45068	UTR_5_PRIME	4.2e-06
2R_12301745_SNP	Sema-2b	INTRON	4.2e-06
2R_12301745_SNP	Menl-2	INTRON	4.2e-06
3R_12990694_SNP	Mur89F	INTRON	4.3e-06
2R_20309307_SNP	prom	INTRON	4.8e-06
3R_9949217_SNP	twf	SYNONYMOUS_CODING	5.6e-06
3R_9949217_SNP	140up	SYNONYMOUS_CODING	5.6e-06
3R_13002842_SNP	Mur89F	INTRON	5.7e-06
2R_20309122_SNP	prom	INTRON	5.8e-06
3R_12997215_SNP	Mur89F	INTRON	6.0e-06
2L_3396579_SNP	CR44792	DOWNSTREAM	6.6e-06
2L_3396577_SNP	CR44792	DOWNSTREAM	6.7e-06
3R_13552010_SNP	Lgr1	INTRON	6.7e-06
3L_4694662_SNP	CG15876	SYNONYMOUS_CODING	7.5e-06
3L_4694662_SNP	RhoGEF64C	SYNONYMOUS_CODING	7.5e-06
X_5639729_SNP	IntS6	INTRON	7.5e-06
2L_2612282_INS	CG15395	DOWNSTREAM	7.6e-06
2R_7024700_SNP	BBS4	SYNONYMOUS_CODING	7.8e-06
2R_20313809_SNP	prom	INTRON	9.0e-06
3L_5853164_SNP			9.6e-06
2L_3885863_SNP	capu	INTRON	9.7e-06

5.4.2 Group count

grps	n
INTRON	38
NON_SYNONYMOUS_CODING	8
SYNONYMOUS_CODING	8
UTR_5_PRIME	4
DOWNSTREAM	3

5.4.3 Gene counts

gene	n
prom	24
CG45068	4
CG45069	4
Mur89F	4
CG18519	2
CR44792	2
Lgr1	2
140up	1
AdamTS-A	1
BBS4	1
bs	1
capu	1
CG14285	1
CG14286	1
CG15395	1
CG15876	1
CG42383	1
CR32773	1
CR44811	1
IntS6	1
Menl-2	1
msl-2	1
Pdsw	1
RhoGEF64C	1
Sema-2b	1
twf	1

5.5 Thermal Breadth

5.5.1 All hits

ID	gene	grps	AvgMixedPval
3R_12992895_SNP	Mur89F	INTRON	1.0e-07
2R_20313579_SNP	prom	INTRON	6.0e-07
2R_20313579_SNP	CG42383	INTRON	6.0e-07
2R_7024700_SNP	BBS4	SYNONYMOUS_CODING	8.0e-07
3R_13900959_SNP			1.3e-06
2R_20301097_SNP	CG45068	SYNONYMOUS_CODING	1.4e-06
2R_20301097_SNP	CG45069	SYNONYMOUS_CODING	1.4e-06
2R_20301239_SNP	CG45068	NON_SYNONYMOUS_CODING	1.4e-06
2R_20301239_SNP	CG45069	NON_SYNONYMOUS_CODING	1.4e-06
2L_2612712_SNP			1.9e-06
3R_13552010_SNP	Lgr1	INTRON	3.0e-06
2R_20301123_SNP	CG45069	UTR_5_PRIME	3.3e-06
2R_20301123_SNP	CG45068	UTR_5_PRIME	3.3e-06
2R_20301091_SNP	CG45069	UTR_5_PRIME	3.4e-06
2R_20301091_SNP	CG45068	UTR_5_PRIME	3.4e-06
3R_5905483_SNP			3.6e-06
X_4385442_SNP	CR32773	INTRON	4.3e-06
3R_13552400_SNP	Lgr1	INTRON	4.5e-06
2L_20784197_SNP			5.6e-06
2L_3465546_SNP	msl-2	NON_SYNONYMOUS_CODING	5.7e-06
2L_3465546_SNP	Pdsw	NON_SYNONYMOUS_CODING	5.7e-06
3R_12991699_SNP	Mur89F	INTRON	6.1e-06
3R_12990694_SNP	Mur89F	INTRON	6.3e-06
3L_997191_SNP	trio	DOWNSTREAM	6.6e-06
3R_4488005_SNP	p	SYNONYMOUS_CODING	7.3e-06
3R_5901971_SNP	CG5361	UPSTREAM	7.3e-06
X_18252257_DEL	CG6106	UPSTREAM	8.1e-06
2R_20250118_SNP	bs	INTRON	9.4e-06
2R_20250118_SNP	CR44811	INTRON	9.4e-06
X_5639729_SNP	IntS6	INTRON	9.6e-06

5.5.2 Group count

grps	n
INTRON	11
NON_SYNONYMOUS_CODING	4
SYNONYMOUS_CODING	4
UTR_5_PRIME	4
UPSTREAM	2
DOWNSTREAM	1

5.5.3 Gene counts

gene	n
CG45068	4
CG45069	4
Mur89F	3
Lgr1	2
BBS4	1
bs	1
CG42383	1
CG5361	1
CG6106	1
CR32773	1
CR44811	1
IntS6	1
msl-2	1
p	1
Pdsw	1
prom	1
trio	1

6 GWAS Tables (pval cutoff 10^-4)

6.1 Summary

GWAS	SNPs	SNPs annotated to genes	Unique genes	Sig DEGs	NS DEGs	No RNAseq data
CTmax	193	169	99	59	39	1
CTmin	348	262	151	72	72	7
ThermalBreadth	358	297	188	NA	NA	188

6.2 Venn Diagram: SNPs & Genes

1. The top GWAS SNPs (10^-4) associated with each phenotype. B. The unique genes associated with those top SNPs

6.2.1 Withouth thermal breadth

1. The top GWAS SNPs (10^-4) associated with each phenotype. B. The unique genes associated with those top SNPs

6.3 CTmax

6.3.1 All hits

ID	gene	grps	AvgMixedPval
2R_10330800_INS	Oaz	INTRON	8.00e-07
2R_6398772_SNP	lola	INTRON	9.00e-07
2R_6398743_SNP	lola	INTRON	9.00e-07
2R_10330805_SNP	Oaz	INTRON	1.00e-06
3R_22515826_SNP			2.30e-06
2L_12384183_SNP	bru-2	INTRON	2.40e-06
3R_25373467_SNP			2.50e-06
2R_17564376_SNP	CG30263	SYNONYMOUS_CODING	2.60e-06
2R_10330722_SNP	Oaz	INTRON	3.00e-06
X_3381582_SNP	CR44999	INTRON	3.20e-06
X_3381582_SNP	CG10803	INTRON	3.20e-06
X_3381590_SNP	CG10803	INTRON	3.20e-06
X_3381590_SNP	CR44999	INTRON	3.20e-06
2R_10330717_SNP	Oaz	INTRON	3.50e-06
X_3381391_SNP	CR44999	INTRON	3.70e-06
X_3381391_SNP	CG10803	INTRON	3.70e-06
X_3381587_SNP	CR44999	INTRON	4.10e-06
X_3381587_SNP	CG10803	INTRON	4.10e-06
3L_9575326_SNP	CG42673	INTRON	6.00e-06
X_5876026_SNP	Grip	INTRON	6.00e-06
3R_3427376_SNP	CG34127	INTRON	7.60e-06
2L_19428598_SNP	CG13085	INTRON	8.40e-06
2L_19428598_SNP	CG16771	INTRON	8.40e-06
2R_10330701_SNP	Oaz	INTRON	9.70e-06
2L_19428336_SNP	CG13085	INTRON	9.90e-06
2L_19428336_SNP	CG16771	INTRON	9.90e-06
3R_20025347_SNP	twin	INTRON	1.00e-05
2R_10330633_INS	Oaz	INTRON	1.02e-05
3L_14419091_SNP	bbg	INTRON	1.03e-05
2R_10330626_SNP	Oaz	INTRON	1.04e-05
2R_10330630_SNP	Oaz	INTRON	1.04e-05
2R_10330637_SNP	Oaz	INTRON	1.04e-05
2L_12339508_INS	CG31862	DOWNSTREAM	1.13e-05
3R_12743515_SNP	iab-8	INTRON	1.18e-05
3R_22504616_SNP	beat-VII	INTRON	1.20e-05
2L_12339516_SNP	CG31862	DOWNSTREAM	1.23e-05
2L_19428576_SNP	CG16771	SYNONYMOUS_CODING	1.24e-05
2L_19428576_SNP	CG13085	SYNONYMOUS_CODING	1.24e-05
2R_10330676_DEL	Oaz	INTRON	1.25e-05
2R_10330688_SNP	Oaz	INTRON	1.25e-05
2R_10330693_SNP	Oaz	INTRON	1.25e-05
2L_19428030_SNP	CG13085	INTRON	1.27e-05
2L_19428030_SNP	CG16771	INTRON	1.27e-05
2L_19437195_SNP	CG10237	INTRON	1.30e-05
2R_10330686_SNP	Oaz	INTRON	1.32e-05
X_10735255_SNP	sbr	INTRON	1.32e-05
X_10735255_SNP	CG15209	INTRON	1.32e-05
X_10735262_INS	sbr	INTRON	1.32e-05
X_10735262_INS	CG15209	INTRON	1.32e-05
2L_12339502_SNP	CG31862	DOWNSTREAM	1.34e-05
2L_19429383_SNP	CG13085	INTRON	1.37e-05
2L_19429383_SNP	CG16771	INTRON	1.37e-05
3L_1853643_SNP	CG13936	INTRON	1.42e-05
2R_10330636_SNP	Oaz	INTRON	1.43e-05
3R_20025331_SNP	twin	INTRON	1.44e-05
3R_22137625_SNP			1.46e-05
X_5876030_SNP	Grip	INTRON	1.48e-05
3R_6790711_SNP			1.56e-05
X_10125128_DEL	Ipod	UTR_3_PRIME	1.59e-05
X_3381972_SNP	CG10803	SYNONYMOUS_CODING	1.60e-05
X_3381972_SNP	CR44999	SYNONYMOUS_CODING	1.60e-05
3R_3427301_SNP	CG34127	INTRON	1.62e-05
2R_10330615_SNP	Oaz	INTRON	1.63e-05
2R_10330665_SNP	Oaz	INTRON	1.70e-05
X_16041977_SNP	disco-r	INTRON	1.70e-05
3L_11137528_SNP	CG32082	INTRON	1.75e-05
3L_22193099_INS	olf413	INTRON	1.75e-05
X_3381054_SNP	CR44999	INTRON	1.78e-05
X_3381054_SNP	CG10803	INTRON	1.78e-05
2L_12384190_SNP	bru-2	INTRON	1.81e-05
X_14256062_SNP	dpr8	INTRON	1.81e-05
2L_19426748_SNP	CG13085	INTRON	1.85e-05
2L_19426748_SNP	CG16771	INTRON	1.85e-05
2L_19426782_SNP	CG16771	INTRON	1.85e-05
2L_19426782_SNP	CG13085	INTRON	1.85e-05
X_14256077_SNP	dpr8	INTRON	1.86e-05
2R_6398430_SNP	lola	INTRON	1.88e-05
X_10735231_INS	sbr	INTRON	1.88e-05
2L_19423677_SNP	Pax	INTRON	1.96e-05
2L_19423677_SNP	CG16771	INTRON	1.96e-05
2L_19429239_SNP	CG13085	INTRON	1.97e-05
2L_19429239_SNP	CG16771	INTRON	1.97e-05
3L_22174657_SNP	olf413	INTRON	2.06e-05
X_14256080_SNP	dpr8	INTRON	2.23e-05
3R_22137592_SNP			2.27e-05
X_3382079_SNP	CG10803	INTRON	2.27e-05
X_3382079_SNP	CR44999	INTRON	2.27e-05
3L_2048836_SNP	sls	SYNONYMOUS_CODING	2.30e-05
2R_17564481_SNP	CG30263	SYNONYMOUS_CODING	2.42e-05
3L_14421116_SNP	bbg	INTRON	2.44e-05
3R_18941021_SNP	Rassf	INTRON	2.59e-05
X_15413373_SNP	Ac13E	INTRON	2.62e-05
2L_19424626_SNP	Pax	INTRON	2.67e-05
2L_19424626_SNP	CG16771	INTRON	2.67e-05
2L_12339554_SNP	CG31862	DOWNSTREAM	2.71e-05
3R_6110171_SNP	CG43143	INTRON	2.75e-05
2L_3243400_SNP			2.92e-05
2R_2894462_SNP	Tsp42Ec	INTRON	2.92e-05
2R_2894462_SNP	CG30160	INTRON	2.92e-05
X_5754038_SNP			2.95e-05
3L_22144030_SNP	olf413	INTRON	3.03e-05
3L_4318551_SNP	Claspin	DOWNSTREAM	3.04e-05
3L_4318551_SNP	CG32250	DOWNSTREAM	3.04e-05
2R_18905268_SNP	twi	INTRON	3.06e-05
2R_18905268_SNP	CG42741	INTRON	3.06e-05
2R_4548600_SNP	ptc	SYNONYMOUS_CODING	3.13e-05
3R_22504742_SNP	beat-VII	INTRON	3.15e-05
2R_10330590_SNP	Oaz	INTRON	3.18e-05
2R_10330596_MNP	Oaz	INTRON	3.18e-05
2R_10330600_INS	Oaz	INTRON	3.18e-05
3L_14339933_SNP	fz	INTRON	3.23e-05
2L_19426685_SNP	CG13085	INTRON	3.39e-05
2L_19426685_SNP	CG16771	INTRON	3.39e-05
3L_22305238_SNP	Ten-m	INTRON	3.43e-05
2R_10330606_SNP	Oaz	INTRON	3.44e-05
2L_15220353_SNP			3.48e-05
3L_16157384_SNP	CG5151	UTR_5_PRIME	3.55e-05
2R_9958844_SNP	Prosap	INTRON	3.56e-05
X_5928662_SNP			3.58e-05
3L_1853640_SNP	CG13936	INTRON	3.62e-05
3R_7950242_SNP	CG4702	INTRON	3.67e-05
3L_14404836_SNP	CG3919	NON_SYNONYMOUS_CODING	3.68e-05
2L_18754429_SNP			3.70e-05
3L_14152568_SNP			3.73e-05
2L_19429322_SNP	CG13085	INTRON	3.78e-05
2L_19429322_SNP	CG16771	INTRON	3.78e-05
2R_10330594_SNP	Oaz	INTRON	3.88e-05
3L_22646528_DEL	CG33772	UPSTREAM	3.91e-05
2L_18754466_SNP			3.93e-05
3R_22805400_SNP	CG14253	INTRON	3.97e-05
2L_18754162_SNP			4.09e-05
3L_16647994_SNP	Baldspot	INTRON	4.12e-05
3L_16647994_SNP	snRNA:U12:73B	INTRON	4.12e-05
3R_23411999_SNP	raps	UTR_3_PRIME	4.13e-05
3R_23411999_SNP	CG5639	UTR_3_PRIME	4.13e-05
2L_12339589_SNP	CG31862	DOWNSTREAM	4.51e-05
3L_1852858_SNP	CG13936	INTRON	4.52e-05
2R_8432371_SNP	fra	INTRON	4.71e-05
2R_8432371_SNP	CG33752	INTRON	4.71e-05
3L_4596471_DEL	Src64B	INTRON	4.74e-05
3R_14376982_SNP			4.74e-05
3R_12743496_SNP	iab-8	INTRON	4.76e-05
X_15304333_SNP	Cngl	INTRON	4.89e-05
X_3382087_SNP	CG10803	INTRON	4.91e-05
X_3382087_SNP	CR44999	INTRON	4.91e-05
2L_18753704_SNP			4.92e-05
3R_22180208_SNP	CG33970	INTRON	5.02e-05
2L_16076386_SNP	beat-Ia	INTRON	5.05e-05
2L_18758119_SNP			5.06e-05
3R_8087122_SNP	svp	INTRON	5.22e-05
3R_8087122_SNP	CG44037	INTRON	5.22e-05
2L_18753902_SNP			5.28e-05
2L_12384172_SNP	bru-2	INTRON	5.31e-05
3R_7950239_SNP	CG4702	INTRON	5.40e-05
2L_8274876_DEL	Btk29A	INTRON	5.42e-05
X_3381344_SNP	CR44999	INTRON	5.55e-05
X_3381344_SNP	CG10803	INTRON	5.55e-05
X_3382189_SNP	CG10803	SYNONYMOUS_CODING	5.67e-05
X_3382189_SNP	CR44999	SYNONYMOUS_CODING	5.67e-05
2L_19425002_SNP	Pax	INTRON	5.85e-05
2L_19425002_SNP	CG16771	INTRON	5.85e-05
3L_22152549_DEL	olf413	INTRON	5.86e-05
3L_14152551_SNP			5.93e-05
2L_15220356_SNP			5.99e-05
2L_19422021_SNP	Pax	INTRON	6.08e-05
3R_8103955_SNP	svp	INTRON	6.10e-05
3R_19830988_DEL	KrT95D	INTRON	6.28e-05
2L_19416856_SNP	Pax	INTRON	6.50e-05
2L_19416856_SNP	Lectin-galC1	INTRON	6.50e-05
3R_24089238_SNP	CG43125	NON_SYNONYMOUS_CODING	6.51e-05
3R_24089238_SNP	CG43124	NON_SYNONYMOUS_CODING	6.51e-05
X_13014365_SNP	CG42237	INTRON	6.67e-05
3L_9575411_SNP	CG42673	INTRON	6.69e-05
3R_20196586_SNP	CG17782	NON_SYNONYMOUS_CODING	6.84e-05
3R_20196586_SNP	CG13614	NON_SYNONYMOUS_CODING	6.84e-05
2R_3514811_SNP	CG43340	INTRON	6.88e-05
2L_19429387_SNP	CG13085	INTRON	6.91e-05
2L_19429387_SNP	CG16771	INTRON	6.91e-05
2L_6742211_SNP	CG11221	UPSTREAM	7.01e-05
X_9642410_SNP	Sp1	INTRON	7.15e-05
X_731454_SNP	CG43867	INTRON	7.22e-05
2R_17565035_SNP	CG30263	SYNONYMOUS_CODING	7.24e-05
3L_19857214_SNP			7.27e-05
3L_14412291_SNP	bbg	INTRON	7.36e-05
3L_3050532_SNP	CG32485	UTR_5_PRIME	7.37e-05
3L_3050532_SNP	Sk2	UTR_5_PRIME	7.37e-05
3L_5608245_SNP			7.42e-05
3L_843314_SNP	Gr61a	INTRON	7.42e-05
3L_843314_SNP	CG13889	INTRON	7.42e-05
X_3381915_SNP	CG10803	SYNONYMOUS_CODING	7.57e-05
X_3381915_SNP	CR44999	SYNONYMOUS_CODING	7.57e-05
2R_17584882_SNP	HmgZ	DOWNSTREAM	7.74e-05
2R_17584882_SNP	CngB	DOWNSTREAM	7.74e-05
X_5671081_SNP	CG42699	INTRON	7.76e-05
X_5671081_SNP	CG3108	INTRON	7.76e-05
2L_12339479_SNP	CG31862	DOWNSTREAM	7.87e-05
2L_6742224_DEL	CG11221	UPSTREAM	7.95e-05
2L_6742213_DEL	CG11221	UPSTREAM	8.21e-05
3R_16565056_SNP	CG17267	UPSTREAM	8.26e-05
3R_16565056_SNP	CG42322	UPSTREAM	8.26e-05
3L_8918810_SNP	Tsp66E	INTRON	8.27e-05
3L_16156405_SNP	CG5151	INTRON	8.30e-05
2R_10330586_SNP	Oaz	INTRON	8.31e-05
2L_14915314_SNP	CG42313	INTRON	8.33e-05
3R_22504708_SNP	beat-VII	INTRON	8.34e-05
3L_6589428_SNP	ndl	NON_SYNONYMOUS_CODING	8.41e-05
3L_10498413_SNP	A2bp1	INTRON	8.48e-05
3L_10498416_MNP	A2bp1	INTRON	8.48e-05
3L_8624605_SNP	Zasp66	INTRON	8.54e-05
3L_8624605_SNP	Cdc6	INTRON	8.54e-05
2R_17588521_MNP	HmgZ	INTRON	8.63e-05
2R_17588521_MNP	HmgD	INTRON	8.63e-05
2R_7460403_SNP			8.63e-05
3L_920622_SNP	Glut1	INTRON	8.69e-05
2L_15220342_INS			8.70e-05
X_7994327_SNP	CG2258	INTRON	8.71e-05
3L_9061593_SNP	CG4911	UTR_3_PRIME	8.76e-05
3R_24785872_SNP	CG14521	INTRON	8.77e-05
X_8790818_SNP	Moe	INTRON	8.79e-05
X_8790829_SNP	Moe	INTRON	8.79e-05
2R_6417213_SNP	lola	INTRON	8.84e-05
3L_19200340_SNP	fz2	INTRON	8.85e-05
X_3382150_SNP	CR44999	INTRON	8.86e-05
X_3382150_SNP	CG10803	INTRON	8.86e-05
3L_14691172_SNP	CG17177	NON_SYNONYMOUS_CODING	8.94e-05
3L_14691172_SNP	ome	NON_SYNONYMOUS_CODING	8.94e-05
3L_2402512_SNP	CG45186	INTRON	9.00e-05
2R_17082950_SNP	Lapsyn	INTRON	9.03e-05
3R_8110301_SNP	svp	INTRON	9.11e-05
3R_17167115_SNP	CG16791	INTRON	9.12e-05
X_7994276_SNP	CG2258	INTRON	9.26e-05
2R_10344322_SNP	Oaz	INTRON	9.29e-05
2R_6426324_SNP	lola	INTRON	9.38e-05
2R_6419048_SNP	lola	DOWNSTREAM	9.42e-05
2L_2552957_SNP	CG3515	UPSTREAM	9.43e-05
X_7994535_SNP	CG2258	INTRON	9.46e-05
2R_10615404_SNP			9.56e-05
2L_12339547_SNP	CG31862	DOWNSTREAM	9.60e-05
3R_27479386_SNP	kek6	INTRON	9.97e-05

6.3.2 Group count

grps	n
INTRON	168
SYNONYMOUS_CODING	13
DOWNSTREAM	12
NON_SYNONYMOUS_CODING	8
UPSTREAM	7
UTR_3_PRIME	4
UTR_5_PRIME	3

6.3.3 Gene counts

gene	n
Oaz	23
CG16771	14
CG10803	12
CR44999	12
CG13085	11
CG31862	7
lola	6
Pax	5
olf413	4
bbg	3
beat-VII	3
bru-2	3
CG11221	3
CG13936	3
CG2258	3
CG30263	3
dpr8	3
sbr	3
svp	3
A2bp1	2
CG15209	2
CG34127	2
CG42673	2
CG4702	2
CG5151	2
Grip	2
HmgZ	2
iab-8	2
Moe	2
twin	2
Ac13E	1
Baldspot	1
beat-Ia	1
Btk29A	1
Cdc6	1
CG10237	1
CG13614	1
CG13889	1
CG14253	1
CG14521	1
CG16791	1
CG17177	1
CG17267	1
CG17782	1
CG30160	1
CG3108	1
CG32082	1
CG32250	1
CG32485	1
CG33752	1
CG33772	1
CG33970	1
CG3515	1
CG3919	1
CG42237	1
CG42313	1
CG42322	1
CG42699	1
CG42741	1
CG43124	1
CG43125	1
CG43143	1
CG43340	1
CG43867	1
CG44037	1
CG45186	1
CG4911	1
CG5639	1
Claspin	1
CngB	1
Cngl	1
disco-r	1
fra	1
fz	1
fz2	1
Glut1	1
Gr61a	1
HmgD	1
Ipod	1
kek6	1
KrT95D	1
Lapsyn	1
Lectin-galC1	1
ndl	1
ome	1
Prosap	1
ptc	1
raps	1
Rassf	1
Sk2	1
sls	1
snRNA:U12:73B	1
Sp1	1
Src64B	1
Ten-m	1
Tsp42Ec	1
Tsp66E	1
twi	1
Zasp66	1

6.4 CTmin

6.4.1 All hits

ID	gene	grps	AvgMixedPval
2R_20313579_SNP	prom	INTRON	0.00e+00
2R_20313579_SNP	CG42383	INTRON	0.00e+00
X_4385442_SNP	CR32773	INTRON	1.00e-07
3R_13900959_SNP			2.00e-07
2R_20308502_SNP	prom	INTRON	4.00e-07
3R_12992895_SNP	Mur89F	INTRON	7.00e-07
2R_20313917_SNP	prom	INTRON	9.00e-07
2R_20313922_DEL	prom	INTRON	9.00e-07
2R_20313930_SNP	prom	INTRON	9.00e-07
2R_20313933_SNP	prom	INTRON	9.00e-07
2R_20313935_INS	prom	INTRON	9.00e-07
2R_20313938_SNP	prom	INTRON	9.00e-07
2R_20313940_MNP	prom	INTRON	9.00e-07
2R_20308558_SNP	prom	INTRON	1.00e-06
2R_20250118_SNP	bs	INTRON	1.00e-06
2R_20250118_SNP	CR44811	INTRON	1.00e-06
2R_20301097_SNP	CG45068	SYNONYMOUS_CODING	1.10e-06
2R_20301097_SNP	CG45069	SYNONYMOUS_CODING	1.10e-06
2R_20301239_SNP	CG45068	NON_SYNONYMOUS_CODING	1.10e-06
2R_20301239_SNP	CG45069	NON_SYNONYMOUS_CODING	1.10e-06
2R_20308533_SNP	prom	INTRON	1.20e-06
2R_20313914_SNP	prom	INTRON	1.30e-06
2L_2612712_SNP			1.40e-06
2R_20313927_SNP	prom	INTRON	1.50e-06
2R_20313911_SNP	prom	INTRON	1.80e-06
2R_20307893_SNP	prom	NON_SYNONYMOUS_CODING	1.80e-06
2R_20313916_SNP	prom	INTRON	1.90e-06
2R_20308565_SNP	prom	INTRON	1.90e-06
2R_20309964_SNP	prom	INTRON	2.00e-06
2R_20309106_SNP	prom	INTRON	2.20e-06
3R_11364111_SNP	CG18519	SYNONYMOUS_CODING	2.20e-06
2R_20313919_SNP	prom	INTRON	2.40e-06
3R_14850882_SNP	CG14285	NON_SYNONYMOUS_CODING	3.10e-06
3R_14850882_SNP	CG14286	NON_SYNONYMOUS_CODING	3.10e-06
2R_20313912_SNP	prom	INTRON	3.20e-06
2L_3465546_SNP	msl-2	NON_SYNONYMOUS_CODING	3.20e-06
2L_3465546_SNP	Pdsw	NON_SYNONYMOUS_CODING	3.20e-06
2R_20301123_SNP	CG45069	UTR_5_PRIME	3.30e-06
2R_20301123_SNP	CG45068	UTR_5_PRIME	3.30e-06
3R_13552400_SNP	Lgr1	INTRON	3.60e-06
3R_11367299_SNP	CG18519	NON_SYNONYMOUS_CODING	4.00e-06
3R_11288771_SNP	AdamTS-A	INTRON	4.20e-06
2R_20301091_SNP	CG45069	UTR_5_PRIME	4.20e-06
2R_20301091_SNP	CG45068	UTR_5_PRIME	4.20e-06
2R_12301745_SNP	Sema-2b	INTRON	4.20e-06
2R_12301745_SNP	Menl-2	INTRON	4.20e-06
3R_12990694_SNP	Mur89F	INTRON	4.30e-06
2R_20309307_SNP	prom	INTRON	4.80e-06
3R_9949217_SNP	twf	SYNONYMOUS_CODING	5.60e-06
3R_9949217_SNP	140up	SYNONYMOUS_CODING	5.60e-06
3R_13002842_SNP	Mur89F	INTRON	5.70e-06
2R_20309122_SNP	prom	INTRON	5.80e-06
3R_12997215_SNP	Mur89F	INTRON	6.00e-06
2L_3396579_SNP	CR44792	DOWNSTREAM	6.60e-06
2L_3396577_SNP	CR44792	DOWNSTREAM	6.70e-06
3R_13552010_SNP	Lgr1	INTRON	6.70e-06
3L_4694662_SNP	CG15876	SYNONYMOUS_CODING	7.50e-06
3L_4694662_SNP	RhoGEF64C	SYNONYMOUS_CODING	7.50e-06
X_5639729_SNP	IntS6	INTRON	7.50e-06
2L_2612282_INS	CG15395	DOWNSTREAM	7.60e-06
2R_7024700_SNP	BBS4	SYNONYMOUS_CODING	7.80e-06
2R_20313809_SNP	prom	INTRON	9.00e-06
3L_5853164_SNP			9.60e-06
2L_3885863_SNP	capu	INTRON	9.70e-06
2R_20263633_SNP	bs	UTR_3_PRIME	1.07e-05
3L_8696154_SNP			1.07e-05
2R_20308557_SNP	prom	INTRON	1.08e-05
2R_20313929_SNP	prom	INTRON	1.11e-05
2L_14847936_SNP	CG15279	INTRON	1.17e-05
X_4385623_SNP	CR32773	INTRON	1.19e-05
3R_11388164_SNP			1.22e-05
2R_15691303_SNP			1.23e-05
2R_20314643_SNP	prom	INTRON	1.26e-05
3L_14188075_SNP	nuf	INTRON	1.30e-05
2R_20250001_SNP	bs	INTRON	1.37e-05
2R_20250001_SNP	CR44811	INTRON	1.37e-05
2R_10963282_SNP			1.40e-05
X_12403029_SNP	CG2556	INTRON	1.43e-05
2R_3769346_SNP	Dgk	UTR_5_PRIME	1.45e-05
3R_5901971_SNP	CG5361	UPSTREAM	1.48e-05
2L_18774061_SNP	ham	INTRON	1.49e-05
2L_18774061_SNP	CR43804	INTRON	1.49e-05
2R_20308551_SNP	prom	INTRON	1.51e-05
2R_20306042_SNP	prom	INTRON	1.52e-05
2R_17037739_INS	CG30389	INTRON	1.55e-05
X_14518598_SNP	NetA	INTRON	1.55e-05
X_6270410_SNP			1.55e-05
3R_12435590_SNP	NPF	INTRON	1.58e-05
3R_12992188_SNP	Mur89F	INTRON	1.61e-05
3L_7002933_SNP	Mp	INTRON	1.80e-05
2R_20280640_SNP	slik	DOWNSTREAM	1.81e-05
X_14991195_SNP	Rab3-GEF	INTRON	1.83e-05
3R_12571587_SNP	bxd	EXON	1.85e-05
3R_9755267_SNP			1.85e-05
X_14994016_SNP	Rab3-GEF	SYNONYMOUS_CODING	1.85e-05
3R_12997318_SNP	Mur89F	INTRON	2.01e-05
2R_20263506_SNP	bs	NON_SYNONYMOUS_CODING	2.02e-05
2R_20263738_SNP	bs	UTR_3_PRIME	2.02e-05
2R_20263740_INS	bs	UTR_3_PRIME	2.02e-05
2R_20263742_SNP	bs	UTR_3_PRIME	2.02e-05
2L_14861293_SNP			2.04e-05
2R_12971842_SNP	CG30460	INTRON	2.08e-05
2R_3772050_SNP	Dgk	INTRON	2.10e-05
3R_11382934_SNP			2.12e-05
2R_20233630_SNP	bs	INTRON	2.14e-05
X_4385497_SNP	CR32773	INTRON	2.14e-05
2R_20304475_SNP	prom	DOWNSTREAM	2.18e-05
2R_20313932_SNP	prom	INTRON	2.19e-05
3R_11367274_SNP	CG18519	SYNONYMOUS_CODING	2.22e-05
3R_11367340_SNP	CG18519	SYNONYMOUS_CODING	2.22e-05
3R_11367346_SNP	CG18519	SYNONYMOUS_CODING	2.22e-05
3R_11423065_SNP			2.25e-05
2R_20257701_SNP	bs	INTRON	2.30e-05
2R_20257701_SNP	CR44811	INTRON	2.30e-05
2R_20303569_SNP	prom	INTRON	2.30e-05
2R_20303569_SNP	CG45068	INTRON	2.30e-05
2L_14829539_SNP			2.36e-05
2R_20252998_SNP	CR44811	INTRON	2.36e-05
2R_20252998_SNP	bs	INTRON	2.36e-05
2L_16629322_SNP	CG42389	INTRON	2.42e-05
2L_16629322_SNP	CR44151	INTRON	2.42e-05
2R_20280846_SNP	slik	DOWNSTREAM	2.43e-05
X_9640945_SNP	Sp1	INTRON	2.43e-05
3R_9755266_SNP			2.54e-05
2R_17103833_SNP	CG15661	SYNONYMOUS_CODING	2.55e-05
3R_12041136_SNP	CR45641	DOWNSTREAM	2.58e-05
X_5908964_SNP	CR44499	DOWNSTREAM	2.58e-05
2R_20308522_SNP	prom	INTRON	2.69e-05
2R_20257613_SNP	bs	INTRON	2.70e-05
2R_20257613_SNP	CR44811	INTRON	2.70e-05
3R_5905483_SNP			2.70e-05
3R_19770578_SNP	CG12268	INTRON	2.74e-05
3R_19770583_SNP	CG12268	INTRON	2.74e-05
3R_19770588_SNP	CG12268	INTRON	2.74e-05
3R_12996262_SNP	Mur89F	INTRON	2.82e-05
3R_4247244_SNP	CG45263	INTRON	2.83e-05
3R_4247244_SNP	Obp85a	INTRON	2.83e-05
3R_9755188_SNP			2.85e-05
2L_1964167_SNP	erm	INTRON	2.87e-05
3L_3637779_SNP	dar1	INTRON	2.88e-05
3R_11422476_INS			2.88e-05
2R_6825968_SNP	Spn47C	UTR_3_PRIME	2.89e-05
2R_20280809_SNP	slik	DOWNSTREAM	2.96e-05
3R_9949202_SNP	twf	SYNONYMOUS_CODING	2.97e-05
3R_9949202_SNP	140up	SYNONYMOUS_CODING	2.97e-05
3R_12992004_SNP	Mur89F	INTRON	2.98e-05
3R_12991699_SNP	Mur89F	INTRON	3.03e-05
X_7604829_INS			3.04e-05
3L_2010684_SNP	CR44535	EXON	3.13e-05
2L_14781915_SNP	CR15280	EXON	3.24e-05
2R_20313730_SNP	prom	INTRON	3.24e-05
3R_13524790_SNP	osa	INTRON	3.26e-05
2R_20260408_SNP	bs	INTRON	3.32e-05
2R_20306197_SNP	prom	SYNONYMOUS_CODING	3.34e-05
2R_12696827_SNP			3.35e-05
3R_5285535_SNP	GstZ2	INTRON	3.36e-05
X_14993421_SNP	Rab3-GEF	INTRON	3.38e-05
X_9662105_SNP			3.43e-05
2R_14565483_DEL	CG44434	DOWNSTREAM	3.45e-05
2R_14565483_DEL	CG44435	DOWNSTREAM	3.45e-05
2R_20296526_SNP	SerT	SYNONYMOUS_CODING	3.51e-05
3R_11400768_SNP			3.51e-05
3R_12992053_DEL	Mur89F	INTRON	3.53e-05
3R_11363907_SNP	CG18519	SYNONYMOUS_CODING	3.58e-05
3R_11363907_SNP	CG18522	SYNONYMOUS_CODING	3.58e-05
2L_1090401_SNP	CG4629	INTRON	3.60e-05
2R_1991490_SNP	EcR	INTRON	3.60e-05
2R_1991491_SNP	EcR	INTRON	3.60e-05
3R_12023256_SNP	sra	UTR_3_PRIME	3.72e-05
3R_12023256_SNP	CG6126	UTR_3_PRIME	3.72e-05
3R_17772582_SNP			3.73e-05
2R_17983519_SNP	CG11073	INTRON	3.78e-05
2R_20269748_SNP	mAChR-A	INTRON	3.81e-05
2L_5945189_SNP	Gpdh	INTRON	3.86e-05
3L_3812775_SNP	CG12006	SYNONYMOUS_CODING	3.86e-05
2L_14829550_SNP			3.88e-05
2L_14861303_SNP			3.90e-05
3L_12306383_SNP			3.90e-05
2R_10963284_SNP			3.96e-05
3L_4254140_SNP	ago	UPSTREAM	3.98e-05
3L_4254140_SNP	CG1265	UPSTREAM	3.98e-05
2L_5613850_SNP	CG14010	INTRON	4.01e-05
2L_2601212_SNP	CR44789	EXON	4.04e-05
2R_20258747_SNP	bs	INTRON	4.07e-05
3R_11405546_SNP			4.24e-05
3R_11411525_SNP			4.28e-05
3R_11425747_SNP			4.31e-05
X_18167335_SNP			4.40e-05
2L_14849951_SNP	CG15279	INTRON	4.44e-05
2R_12704274_SNP	CG5550	SYNONYMOUS_CODING	4.44e-05
2R_12704274_SNP	CR43417	SYNONYMOUS_CODING	4.44e-05
3L_4694906_SNP	RhoGEF64C	INTRON	4.44e-05
3L_4694906_SNP	CG15876	INTRON	4.44e-05
2R_1618770_SNP			4.47e-05
2R_20306103_SNP	prom	INTRON	4.48e-05
3R_12996121_SNP	Mur89F	INTRON	4.64e-05
X_12899932_SNP	rad	INTRON	4.64e-05
3R_9755209_INS			4.69e-05
X_14994013_SNP	Rab3-GEF	SYNONYMOUS_CODING	4.71e-05
X_14994019_SNP	Rab3-GEF	SYNONYMOUS_CODING	4.71e-05
3R_13928920_SNP	sr	INTRON	4.73e-05
3L_997191_SNP	trio	DOWNSTREAM	4.76e-05
3L_4254108_SNP	ago	INTRON	4.78e-05
3L_4254108_SNP	CG1265	INTRON	4.78e-05
3R_11420351_SNP			4.82e-05
3R_11420344_SNP			4.83e-05
2L_5964548_SNP	psd	INTRON	4.87e-05
2L_5964548_SNP	CG13992	INTRON	4.87e-05
3R_9755183_INS			4.87e-05
3R_12996202_SNP	Mur89F	INTRON	4.91e-05
2R_12628367_SNP			4.92e-05
3L_3812970_SNP	CG12006	SYNONYMOUS_CODING	4.94e-05
X_18251508_DEL			4.94e-05
X_3945990_SNP			5.00e-05
2R_20257397_SNP	bs	INTRON	5.01e-05
2R_20257397_SNP	CR44811	INTRON	5.01e-05
2L_14839600_SNP	CR43805	DOWNSTREAM	5.07e-05
2R_5227902_SNP	CG13954	INTRON	5.08e-05
2R_5227902_SNP	CG13739	INTRON	5.08e-05
3R_12992010_SNP	Mur89F	INTRON	5.11e-05
3R_12996231_DEL	Mur89F	INTRON	5.17e-05
3R_19565063_SNP	Hmgcr	INTRON	5.18e-05
4_212564_SNP	CG2316	INTRON	5.18e-05
3R_10974341_SNP			5.24e-05
2L_8257947_SNP	Btk29A	DOWNSTREAM	5.27e-05
2L_8257947_SNP	CG8086	DOWNSTREAM	5.27e-05
3R_9755264_SNP			5.32e-05
3R_11384632_SNP			5.36e-05
3L_12833443_SNP	CG10960	INTRON	5.37e-05
X_18915078_SNP	CG43759	INTRON	5.38e-05
2L_3013371_SNP	CG17265	INTRON	5.49e-05
3L_16500200_SNP	CG43373	INTRON	5.52e-05
2R_20276477_SNP	mAChR-A	INTRON	5.61e-05
3L_8207415_SNP	CG8006	DOWNSTREAM	5.61e-05
3L_8207415_SNP	CG8012	DOWNSTREAM	5.61e-05
2R_9189361_DEL	CG17047	DOWNSTREAM	5.62e-05
X_14993547_SNP	Rab3-GEF	INTRON	5.63e-05
2L_5867252_SNP	rau	INTRON	5.64e-05
2L_1430353_SNP			5.65e-05
2R_20298783_SNP	SerT	UPSTREAM	5.67e-05
2R_20298783_SNP	CG45068	UPSTREAM	5.67e-05
2R_20301145_SNP	CG45068	SYNONYMOUS_CODING	5.70e-05
2R_20301145_SNP	CG45069	SYNONYMOUS_CODING	5.70e-05
2R_3551128_SNP	CG2065	UPSTREAM	5.71e-05
2R_3551128_SNP	CG2070	UPSTREAM	5.71e-05
3L_11835004_SNP			5.72e-05
X_6297829_SNP			5.74e-05
2L_14839047_SNP			5.78e-05
2L_14839838_SNP	CR43805	DOWNSTREAM	5.78e-05
2R_17118453_SNP	ASPP	INTRON	5.88e-05
2R_20263548_SNP	bs	UTR_3_PRIME	5.91e-05
3R_11405178_SNP			5.92e-05
3R_12989857_SNP	Mur89F	INTRON	5.92e-05
X_18167373_DEL			5.92e-05
2L_14839629_INS	CR43805	DOWNSTREAM	5.96e-05
2R_20300858_SNP	CG45068	SYNONYMOUS_CODING	5.98e-05
2R_20300858_SNP	CG45069	SYNONYMOUS_CODING	5.98e-05
3R_13900852_SNP			6.03e-05
3R_13900177_SNP			6.08e-05
X_18251504_SNP			6.09e-05
X_18251505_SNP			6.09e-05
3R_11420325_SNP			6.24e-05
3L_4254603_DEL	CG1265	UPSTREAM	6.26e-05
3L_4254603_DEL	ago	UPSTREAM	6.26e-05
2R_9926382_SNP	mam	SYNONYMOUS_CODING	6.31e-05
3R_11420346_SNP			6.32e-05
3R_11402243_SNP			6.37e-05
3R_12996042_SNP	Mur89F	INTRON	6.39e-05
2R_17798495_SNP	Fili	INTRON	6.40e-05
2L_14840839_SNP	CR43805	DOWNSTREAM	6.45e-05
3R_11425064_SNP			6.45e-05
2R_12628349_SNP			6.46e-05
2R_16139285_SNP	CG9864	INTRON	6.51e-05
2R_20258970_SNP	bs	INTRON	6.51e-05
3R_11420330_SNP			6.52e-05
3R_11422667_SNP			6.52e-05
2R_12009356_SNP	Jhe	NON_SYNONYMOUS_CODING	6.54e-05
X_7588127_SNP	CHES-1-like	INTRON	6.66e-05
3R_5724642_SNP	Glut4EF	INTRON	6.72e-05
3R_24617170_SNP	intr	UTR_3_PRIME	6.75e-05
3R_24617170_SNP	CG34295	UTR_3_PRIME	6.75e-05
3R_19770553_SNP	CG12268	INTRON	6.76e-05
2R_19373351_SNP	CG43795	INTRON	6.81e-05
3R_12988032_SNP	Mur89F	INTRON	6.82e-05
3R_11367310_SNP	CG18519	NON_SYNONYMOUS_CODING	6.84e-05
X_18252257_DEL	CG6106	UPSTREAM	6.92e-05
3L_4671269_SNP	axo	INTRON	7.01e-05
2R_10962869_SNP			7.03e-05
3R_12996058_SNP	Mur89F	INTRON	7.07e-05
2R_3772313_SNP	Dgk	INTRON	7.10e-05
3L_13383636_SNP	Poc1	UPSTREAM	7.10e-05
2R_18750111_SNP			7.21e-05
X_18252738_DEL	CG6106	UPSTREAM	7.21e-05
X_18252748_SNP	CG6106	UPSTREAM	7.21e-05
2L_14847382_SNP	CG15279	INTRON	7.26e-05
2R_6825911_SNP	Spn47C	DOWNSTREAM	7.26e-05
3R_11420431_DEL			7.26e-05
2R_9208823_SNP			7.29e-05
X_5631703_INS	CG32758	UTR_5_PRIME	7.32e-05
X_5631703_INS	IntS6	UTR_5_PRIME	7.32e-05
2L_14840782_SNP	CR43805	DOWNSTREAM	7.33e-05
2L_14840900_SNP	CR43805	DOWNSTREAM	7.33e-05
3R_11347985_SNP			7.35e-05
3R_11355047_SNP	CG31296	DOWNSTREAM	7.36e-05
X_16295460_SNP	CG9981	SYNONYMOUS_CODING	7.45e-05
X_18167332_SNP			7.47e-05
2L_1264510_SNP	robo3	INTRON	7.48e-05
2R_13598343_SNP	CG6424	INTRON	7.51e-05
2L_20784197_SNP			7.52e-05
3R_9755191_SNP			7.56e-05
3R_9755213_SNP			7.60e-05
2R_20253495_SNP	CR44811	INTRON	7.63e-05
2R_20253495_SNP	bs	INTRON	7.63e-05
3R_11367384_SNP	CG18519	NON_SYNONYMOUS_CODING	7.63e-05
2L_1611896_SNP	CG14352	INTRON	7.65e-05
2L_1611896_SNP	RFeSP	INTRON	7.65e-05
X_12346699_SNP	Pkcdelta	INTRON	7.65e-05
2R_19373299_SNP	CG43795	INTRON	7.69e-05
2L_14850088_SNP	CG15279	INTRON	7.76e-05
3R_12959441_SNP	CG31266	UTR_3_PRIME	7.84e-05
3R_12959441_SNP	CG31267	UTR_3_PRIME	7.84e-05
3R_12998775_SNP	Mur89F	INTRON	7.88e-05
3R_11420305_SNP			7.93e-05
2R_20305957_SNP	prom	INTRON	7.95e-05
2L_5942852_SNP	Sfp26Ad	SYNONYMOUS_CODING	7.99e-05
2L_5942852_SNP	CR45289	SYNONYMOUS_CODING	7.99e-05
3L_18019988_SNP	Eip75B	INTRON	8.11e-05
3L_9933694_SNP	CG34356	INTRON	8.16e-05
2R_12628403_SNP			8.20e-05
3R_9755255_SNP			8.20e-05
X_3945994_SNP			8.25e-05
3R_6961146_SNP			8.26e-05
2R_10221274_SNP	Shroom	INTRON	8.41e-05
3R_12733232_SNP	iab-8	INTRON	8.42e-05
3R_12733233_SNP	iab-8	INTRON	8.42e-05
3R_12733519_SNP	iab-8	INTRON	8.42e-05
3R_11420324_SNP			8.45e-05
2R_20275800_SNP	mAChR-A	INTRON	8.46e-05
3R_14277461_SNP	fru	INTRON	8.46e-05
2L_14861260_SNP			8.49e-05
X_3256422_SNP			8.50e-05
X_3256427_SNP			8.50e-05
3L_7607016_SNP	CG33275	INTRON	8.52e-05
3L_9760566_SNP	CG8177	INTRON	8.56e-05
2R_16825523_SNP	Rx	DOWNSTREAM	8.57e-05
3L_9933685_SNP	CG34356	INTRON	8.58e-05
3R_11424706_SNP			8.60e-05
2R_3772109_INS	Dgk	INTRON	8.63e-05
3R_12317718_SNP	Cad89D	SYNONYMOUS_CODING	8.63e-05
2R_20261326_SNP	bs	INTRON	8.69e-05
2R_20261326_SNP	tRNA:N5:60C	INTRON	8.69e-05
3R_11387717_SNP			8.69e-05
X_14991448_SNP	Rab3-GEF	INTRON	8.80e-05
2R_20284940_SNP	slik	SYNONYMOUS_CODING	8.82e-05
2R_20260586_SNP	bs	INTRON	8.86e-05
2R_20260586_SNP	tRNA:N5:60C	INTRON	8.86e-05
X_14993353_SNP	Rab3-GEF	INTRON	8.87e-05
3L_14972722_INS	CG3349	UTR_5_PRIME	8.90e-05
3R_12996167_SNP	Mur89F	INTRON	8.94e-05
3R_14287775_SNP	fru	INTRON	8.94e-05
3R_11388712_SNP			8.96e-05
2L_2782146_INS	Syt1	UTR_3_PRIME	8.98e-05
X_14991551_SNP	Rab3-GEF	SYNONYMOUS_CODING	9.04e-05
3L_15704758_SNP			9.07e-05
2L_17027312_SNP			9.09e-05
2L_4353069_SNP	CG15429	SYNONYMOUS_CODING	9.11e-05
3R_11292329_SNP	AdamTS-A	INTRON	9.16e-05
2R_12559097_DEL	CG34457	UTR_3_PRIME	9.18e-05
2R_12559097_DEL	CG34458	UTR_3_PRIME	9.18e-05
2R_20276009_SNP	mAChR-A	INTRON	9.18e-05
2L_14858849_SNP			9.20e-05
2R_20264927_SNP	CG13578	UPSTREAM	9.20e-05
2R_20264927_SNP	bs	UPSTREAM	9.20e-05
3L_12404345_SNP	CG32103	INTRON	9.20e-05
3R_12989856_SNP	Mur89F	INTRON	9.22e-05
X_19504387_DEL	CG14207	INTRON	9.33e-05
2R_10218531_SNP	Shroom	INTRON	9.35e-05
2L_8325829_SNP	CG7781	UPSTREAM	9.38e-05
3L_17618385_SNP	CG7510	INTRON	9.38e-05
3R_13332029_SNP	Dscam3	UPSTREAM	9.38e-05
2R_3546887_SNP	CG1339	SYNONYMOUS_CODING	9.40e-05
2R_3546887_SNP	CG30495	SYNONYMOUS_CODING	9.40e-05
2R_16938611_SNP	shg	SYNONYMOUS_CODING	9.41e-05
3R_12992033_SNP	Mur89F	INTRON	9.45e-05
2L_9735509_SNP	Nckx30C	INTRON	9.47e-05
X_14991393_DEL	Rab3-GEF	INTRON	9.47e-05
3R_11379202_SNP	CG18516	UPSTREAM	9.48e-05
2R_20277886_SNP	mAChR-A	UPSTREAM	9.51e-05
2R_20277886_SNP	CR44813	UPSTREAM	9.51e-05
3R_11400817_SNP			9.64e-05
2L_14839669_SNP	CR43805	DOWNSTREAM	9.70e-05
3R_11402209_SNP			9.76e-05
3R_12996226_SNP	Mur89F	INTRON	9.79e-05
3R_12396134_SNP	CG42342	INTRON	9.90e-05
3L_3684685_DEL			9.93e-05
2L_21033767_SNP	CG42238	INTRON	9.98e-05
2R_8722614_SNP			9.99e-05

6.4.2 Group count

grps	n
INTRON	185
SYNONYMOUS_CODING	40
DOWNSTREAM	27
UPSTREAM	20
UTR_3_PRIME	15
NON_SYNONYMOUS_CODING	12
UTR_5_PRIME	8
EXON	4

6.4.3 Gene counts

gene	n
prom	37
Mur89F	23
bs	20
Rab3-GEF	10
CG18519	8
CG45068	8
CR43805	7
CR44811	7
CG45069	6
mAChR-A	5
CG12268	4
CG15279	4
Dgk	4
slik	4
ago	3
CG1265	3
CG6106	3
CR32773	3
iab-8	3
140up	2
AdamTS-A	2
CG12006	2
CG15876	2
CG34356	2
CG43795	2
CR44792	2
EcR	2
fru	2
IntS6	2
Lgr1	2
RhoGEF64C	2
SerT	2
Shroom	2
Spn47C	2
tRNA:N5:60C	2
twf	2
ASPP	1
axo	1
BBS4	1
Btk29A	1
bxd	1
Cad89D	1
capu	1
CG10960	1
CG11073	1
CG1339	1
CG13578	1
CG13739	1
CG13954	1
CG13992	1
CG14010	1
CG14207	1
CG14285	1
CG14286	1
CG14352	1
CG15395	1
CG15429	1
CG15661	1
CG17047	1
CG17265	1
CG18516	1
CG18522	1
CG2065	1
CG2070	1
CG2316	1
CG2556	1
CG30389	1
CG30460	1
CG30495	1
CG31266	1
CG31267	1
CG31296	1
CG32103	1
CG32758	1
CG33275	1
CG3349	1
CG34295	1
CG34457	1
CG34458	1
CG42238	1
CG42342	1
CG42383	1
CG42389	1
CG43373	1
CG43759	1
CG44434	1
CG44435	1
CG45263	1
CG4629	1
CG5361	1
CG5550	1
CG6126	1
CG6424	1
CG7510	1
CG7781	1
CG8006	1
CG8012	1
CG8086	1
CG8177	1
CG9864	1
CG9981	1
CHES-1-like	1
CR15280	1
CR43417	1
CR43804	1
CR44151	1
CR44499	1
CR44535	1
CR44789	1
CR44813	1
CR45289	1
CR45641	1
dar1	1
Dscam3	1
Eip75B	1
erm	1
Fili	1
Glut4EF	1
Gpdh	1
GstZ2	1
ham	1
Hmgcr	1
intr	1
Jhe	1
mam	1
Menl-2	1
Mp	1
msl-2	1
Nckx30C	1
NetA	1
NPF	1
nuf	1
Obp85a	1
osa	1
Pdsw	1
Pkcdelta	1
Poc1	1
psd	1
rad	1
rau	1
RFeSP	1
robo3	1
Rx	1
Sema-2b	1
Sfp26Ad	1
shg	1
Sp1	1
sr	1
sra	1
Syt1	1
trio	1

6.5 Thermal Breadth

6.5.1 All hits

ID	gene	grps	AvgMixedPval
3R_12992895_SNP	Mur89F	INTRON	1.00e-07
2R_20313579_SNP	prom	INTRON	6.00e-07
2R_20313579_SNP	CG42383	INTRON	6.00e-07
2R_7024700_SNP	BBS4	SYNONYMOUS_CODING	8.00e-07
3R_13900959_SNP			1.30e-06
2R_20301097_SNP	CG45068	SYNONYMOUS_CODING	1.40e-06
2R_20301097_SNP	CG45069	SYNONYMOUS_CODING	1.40e-06
2R_20301239_SNP	CG45068	NON_SYNONYMOUS_CODING	1.40e-06
2R_20301239_SNP	CG45069	NON_SYNONYMOUS_CODING	1.40e-06
2L_2612712_SNP			1.90e-06
3R_13552010_SNP	Lgr1	INTRON	3.00e-06
2R_20301123_SNP	CG45069	UTR_5_PRIME	3.30e-06
2R_20301123_SNP	CG45068	UTR_5_PRIME	3.30e-06
2R_20301091_SNP	CG45069	UTR_5_PRIME	3.40e-06
2R_20301091_SNP	CG45068	UTR_5_PRIME	3.40e-06
3R_5905483_SNP			3.60e-06
X_4385442_SNP	CR32773	INTRON	4.30e-06
3R_13552400_SNP	Lgr1	INTRON	4.50e-06
2L_20784197_SNP			5.60e-06
2L_3465546_SNP	msl-2	NON_SYNONYMOUS_CODING	5.70e-06
2L_3465546_SNP	Pdsw	NON_SYNONYMOUS_CODING	5.70e-06
3R_12991699_SNP	Mur89F	INTRON	6.10e-06
3R_12990694_SNP	Mur89F	INTRON	6.30e-06
3L_997191_SNP	trio	DOWNSTREAM	6.60e-06
3R_4488005_SNP	p	SYNONYMOUS_CODING	7.30e-06
3R_5901971_SNP	CG5361	UPSTREAM	7.30e-06
X_18252257_DEL	CG6106	UPSTREAM	8.10e-06
2R_20250118_SNP	bs	INTRON	9.40e-06
2R_20250118_SNP	CR44811	INTRON	9.40e-06
X_5639729_SNP	IntS6	INTRON	9.60e-06
3L_7002933_SNP	Mp	INTRON	1.01e-05
2R_17983519_SNP	CG11073	INTRON	1.10e-05
3R_4487071_SNP	p	NON_SYNONYMOUS_CODING	1.11e-05
3R_4487071_SNP	bel	NON_SYNONYMOUS_CODING	1.11e-05
2R_14565483_DEL	CG44434	DOWNSTREAM	1.15e-05
2R_14565483_DEL	CG44435	DOWNSTREAM	1.15e-05
2R_20308502_SNP	prom	INTRON	1.18e-05
2R_17103833_SNP	CG15661	SYNONYMOUS_CODING	1.29e-05
3R_12997215_SNP	Mur89F	INTRON	1.29e-05
3R_17312898_SNP	CG7922	SYNONYMOUS_CODING	1.31e-05
3R_12317718_SNP	Cad89D	SYNONYMOUS_CODING	1.33e-05
X_9640945_SNP	Sp1	INTRON	1.33e-05
2R_11082462_SNP	CG43829	UPSTREAM	1.39e-05
2L_14847936_SNP	CG15279	INTRON	1.40e-05
3R_4247244_SNP	CG45263	INTRON	1.45e-05
3R_4247244_SNP	Obp85a	INTRON	1.45e-05
3R_12992188_SNP	Mur89F	INTRON	1.48e-05
X_18251508_DEL			1.49e-05
2L_18774061_SNP	ham	INTRON	1.53e-05
2L_18774061_SNP	CR43804	INTRON	1.53e-05
2R_20313919_SNP	prom	INTRON	1.53e-05
3R_17312919_SNP	CG7922	SYNONYMOUS_CODING	1.60e-05
3R_12985727_SNP	Mur89F	INTRON	1.63e-05
2L_2612282_INS	CG15395	DOWNSTREAM	1.65e-05
2R_20313917_SNP	prom	INTRON	1.67e-05
2R_20313922_DEL	prom	INTRON	1.67e-05
2R_20313930_SNP	prom	INTRON	1.67e-05
2R_20313933_SNP	prom	INTRON	1.67e-05
2R_20313935_INS	prom	INTRON	1.67e-05
2R_20313938_SNP	prom	INTRON	1.67e-05
2R_20313940_MNP	prom	INTRON	1.67e-05
2R_20308565_SNP	prom	INTRON	1.69e-05
X_18251504_SNP			1.69e-05
X_18251505_SNP			1.69e-05
3L_4694906_SNP	RhoGEF64C	INTRON	1.71e-05
3L_4694906_SNP	CG15876	INTRON	1.71e-05
2R_17037739_INS	CG30389	INTRON	1.72e-05
2R_1991490_SNP	EcR	INTRON	1.85e-05
2R_1991491_SNP	EcR	INTRON	1.85e-05
3L_12833443_SNP	CG10960	INTRON	1.87e-05
2L_7751402_SNP	CG7203	DOWNSTREAM	1.91e-05
3R_22095003_SNP	CG6154	INTRON	1.91e-05
2R_20308558_SNP	prom	INTRON	1.92e-05
2L_9792840_SNP	CG13123	INTRON	1.93e-05
2L_9792840_SNP	nAChRalpha6	INTRON	1.93e-05
3L_5853164_SNP			1.96e-05
3R_12992004_SNP	Mur89F	INTRON	2.03e-05
2R_5227902_SNP	CG13954	INTRON	2.05e-05
2R_5227902_SNP	CG13739	INTRON	2.05e-05
2R_3551128_SNP	CG2065	UPSTREAM	2.07e-05
2R_3551128_SNP	CG2070	UPSTREAM	2.07e-05
2R_3546887_SNP	CG1339	SYNONYMOUS_CODING	2.09e-05
2R_3546887_SNP	CG30495	SYNONYMOUS_CODING	2.09e-05
X_14994016_SNP	Rab3-GEF	SYNONYMOUS_CODING	2.11e-05
X_9641804_SNP	Sp1	INTRON	2.12e-05
3R_19565063_SNP	Hmgcr	INTRON	2.13e-05
2R_20313914_SNP	prom	INTRON	2.16e-05
2R_20313927_SNP	prom	INTRON	2.16e-05
X_9641643_SNP	Sp1	INTRON	2.17e-05
3R_9755267_SNP			2.25e-05
3R_9949217_SNP	twf	SYNONYMOUS_CODING	2.25e-05
3R_9949217_SNP	140up	SYNONYMOUS_CODING	2.25e-05
X_12403029_SNP	CG2556	INTRON	2.26e-05
3L_4694662_SNP	CG15876	SYNONYMOUS_CODING	2.27e-05
3L_4694662_SNP	RhoGEF64C	SYNONYMOUS_CODING	2.27e-05
2R_20308533_SNP	prom	INTRON	2.30e-05
X_9641727_SNP	Sp1	INTRON	2.31e-05
3R_11367299_SNP	CG18519	NON_SYNONYMOUS_CODING	2.32e-05
3R_13448666_DEL	tRNA:CR33534	DOWNSTREAM	2.37e-05
3R_13448666_DEL	CG14323	DOWNSTREAM	2.37e-05
3L_8696154_SNP			2.44e-05
2R_20313916_SNP	prom	INTRON	2.46e-05
X_7604829_INS			2.52e-05
3L_3844015_SNP			2.63e-05
3R_12992053_DEL	Mur89F	INTRON	2.66e-05
2R_20309106_SNP	prom	INTRON	2.67e-05
3R_12997318_SNP	Mur89F	INTRON	2.67e-05
2L_9508608_SNP	CG33298	INTRON	2.71e-05
2L_1964167_SNP	erm	INTRON	2.72e-05
3L_16725026_SNP			2.81e-05
3R_12992010_SNP	Mur89F	INTRON	2.85e-05
2R_20313911_SNP	prom	INTRON	2.86e-05
X_18167373_DEL			2.88e-05
3R_13418241_SNP			2.89e-05
3R_24617170_SNP	intr	UTR_3_PRIME	2.93e-05
3R_24617170_SNP	CG34295	UTR_3_PRIME	2.93e-05
X_6297829_SNP			2.93e-05
3R_9755266_SNP			2.97e-05
3R_11388164_SNP			2.99e-05
2R_12230279_SNP	CG7997	INTRON	3.02e-05
X_13151875_SNP	mew	INTRON	3.03e-05
X_13151875_SNP	CG15742	INTRON	3.03e-05
2R_8502479_SNP	CG45086	INTRON	3.05e-05
2R_8502479_SNP	Galphaq	INTRON	3.05e-05
3L_4694850_SNP	RhoGEF64C	INTRON	3.07e-05
3L_4694850_SNP	CG15876	INTRON	3.07e-05
3R_12992033_SNP	Mur89F	INTRON	3.07e-05
2L_3885863_SNP	capu	INTRON	3.08e-05
2R_7752530_SNP	CG42531	DOWNSTREAM	3.09e-05
2R_7752530_SNP	Damm	DOWNSTREAM	3.09e-05
2L_7751417_SNP	CG7203	DOWNSTREAM	3.10e-05
2L_5964548_SNP	psd	INTRON	3.13e-05
2L_5964548_SNP	CG13992	INTRON	3.13e-05
3R_13900177_SNP			3.14e-05
3R_13131971_SNP			3.19e-05
X_18167335_SNP			3.19e-05
X_7587146_DEL	CHES-1-like	INTRON	3.36e-05
X_3376568_SNP	CR44999	INTRON	3.38e-05
X_3376568_SNP	CG10804	INTRON	3.38e-05
2R_20263548_SNP	bs	UTR_3_PRIME	3.40e-05
2L_7751376_SNP	CG7203	DOWNSTREAM	3.41e-05
2L_7751399_SNP	CG7203	DOWNSTREAM	3.42e-05
2R_12628367_SNP			3.46e-05
2R_7023942_SNP	BBS4	INTRON	3.50e-05
2R_7023949_SNP	BBS4	INTRON	3.50e-05
2R_7023958_SNP	BBS4	INTRON	3.50e-05
2R_7023976_SNP	BBS4	INTRON	3.50e-05
3R_17309679_SNP	CG7922	NON_SYNONYMOUS_CODING	3.50e-05
2R_12369476_SNP			3.52e-05
X_18251526_SNP			3.53e-05
3R_4313545_SNP			3.54e-05
2L_5867252_SNP	rau	INTRON	3.61e-05
3R_13524790_SNP	osa	INTRON	3.61e-05
X_14993421_SNP	Rab3-GEF	INTRON	3.63e-05
2R_20263633_SNP	bs	UTR_3_PRIME	3.71e-05
3R_13332029_SNP	Dscam3	UPSTREAM	3.71e-05
X_7588127_SNP	CHES-1-like	INTRON	3.74e-05
3R_11364111_SNP	CG18519	SYNONYMOUS_CODING	3.75e-05
X_18251390_SNP			3.75e-05
2R_20307893_SNP	prom	NON_SYNONYMOUS_CODING	3.76e-05
3R_12435590_SNP	NPF	INTRON	3.76e-05
3R_19770578_SNP	CG12268	INTRON	3.84e-05
3R_19770583_SNP	CG12268	INTRON	3.84e-05
3R_19770588_SNP	CG12268	INTRON	3.84e-05
3L_2294717_SNP	MsR2	INTRON	3.86e-05
3R_11129613_SNP	Tm1	INTRON	3.90e-05
X_6297782_SNP			3.98e-05
3R_5824500_SNP	Spn85F	NON_SYNONYMOUS_CODING	3.99e-05
3R_5824500_SNP	CG5359	NON_SYNONYMOUS_CODING	3.99e-05
X_18252264_SNP	CG6106	UPSTREAM	4.04e-05
X_5631703_INS	CG32758	UTR_5_PRIME	4.04e-05
X_5631703_INS	IntS6	UTR_5_PRIME	4.04e-05
3R_10655623_SNP	btsz	INTRON	4.07e-05
2L_7751543_DEL	CG7203	DOWNSTREAM	4.08e-05
3L_2293540_SNP	MsR2	INTRON	4.09e-05
2R_12628349_SNP			4.11e-05
3R_13002842_SNP	Mur89F	INTRON	4.12e-05
2R_12218440_SNP	Vha44	INTRON	4.14e-05
3R_22094891_DEL	CG6154	INTRON	4.17e-05
4_212564_SNP	CG2316	INTRON	4.17e-05
3R_11288771_SNP	AdamTS-A	INTRON	4.21e-05
3L_3812775_SNP	CG12006	SYNONYMOUS_CODING	4.23e-05
2R_7752475_SNP	CG42531	DOWNSTREAM	4.24e-05
2R_7752475_SNP	Damm	DOWNSTREAM	4.24e-05
2R_8722614_SNP			4.28e-05
X_18252738_DEL	CG6106	UPSTREAM	4.28e-05
X_18252748_SNP	CG6106	UPSTREAM	4.28e-05
X_18251456_SNP			4.32e-05
2R_20309964_SNP	prom	INTRON	4.33e-05
2R_12628403_SNP			4.36e-05
2R_20263506_SNP	bs	NON_SYNONYMOUS_CODING	4.36e-05
2R_20263738_SNP	bs	UTR_3_PRIME	4.36e-05
2R_20263740_INS	bs	UTR_3_PRIME	4.36e-05
2R_20263742_SNP	bs	UTR_3_PRIME	4.36e-05
2R_20309307_SNP	prom	INTRON	4.37e-05
X_14994013_SNP	Rab3-GEF	SYNONYMOUS_CODING	4.37e-05
X_14994019_SNP	Rab3-GEF	SYNONYMOUS_CODING	4.37e-05
2R_2998199_SNP	esn	INTRON	4.46e-05
3R_22081036_SNP	Ald	DOWNSTREAM	4.46e-05
2R_20301145_SNP	CG45068	SYNONYMOUS_CODING	4.47e-05
2R_20301145_SNP	CG45069	SYNONYMOUS_CODING	4.47e-05
3L_6639773_SNP			4.47e-05
2R_20313912_SNP	prom	INTRON	4.51e-05
3L_14197669_SNP	nuf	INTRON	4.54e-05
3L_14197669_SNP	CG32141	INTRON	4.54e-05
X_4985802_SNP	CG15465	INTRON	4.56e-05
X_4985802_SNP	rg	INTRON	4.56e-05
3L_3329652_SNP	CR45380	DOWNSTREAM	4.62e-05
3L_3329652_SNP	CG14961	DOWNSTREAM	4.62e-05
3R_13419831_SNP	CG7587	UPSTREAM	4.63e-05
2R_16825523_SNP	Rx	DOWNSTREAM	4.64e-05
3R_14850882_SNP	CG14285	NON_SYNONYMOUS_CODING	4.64e-05
3R_14850882_SNP	CG14286	NON_SYNONYMOUS_CODING	4.64e-05
3L_3812970_SNP	CG12006	SYNONYMOUS_CODING	4.66e-05
2L_3396579_SNP	CR44792	DOWNSTREAM	4.67e-05
3R_17309591_SNP	CG7922	INTRON	4.67e-05
3R_17314258_DEL			4.68e-05
X_12899932_SNP	rad	INTRON	4.68e-05
X_4986248_DEL	CG15465	INTRON	4.74e-05
X_4986248_DEL	rg	INTRON	4.74e-05
2R_20269748_SNP	mAChR-A	INTRON	4.79e-05
2L_16699438_SNP	grp	NON_SYNONYMOUS_CODING	4.81e-05
2L_16699438_SNP	CR43669	NON_SYNONYMOUS_CODING	4.81e-05
2R_12451205_DEL	DAT	INTRON	4.81e-05
3L_7607016_SNP	CG33275	INTRON	4.82e-05
3R_9755264_SNP			4.83e-05
2L_1611896_SNP	CG14352	INTRON	4.85e-05
2L_1611896_SNP	RFeSP	INTRON	4.85e-05
2R_14222653_DEL	sbb	INTRON	4.87e-05
2L_3396577_SNP	CR44792	DOWNSTREAM	4.89e-05
3L_14092468_SNP			4.89e-05
3R_10974341_SNP			4.94e-05
X_5656121_SNP	MAPk-Ak2	INTRON	4.94e-05
3L_9760566_SNP	CG8177	INTRON	4.96e-05
X_20907278_SNP	Ntf-2	INTRON	4.97e-05
X_20907279_SNP	Ntf-2	INTRON	4.97e-05
3R_17309145_SNP	CG7922	SYNONYMOUS_CODING	4.98e-05
2R_20313730_SNP	prom	INTRON	5.01e-05
2L_2592883_SNP	CG15394	DOWNSTREAM	5.04e-05
3L_14188075_SNP	nuf	INTRON	5.09e-05
X_18167332_SNP			5.14e-05
3R_17313012_SNP	CG7922	DOWNSTREAM	5.15e-05
2L_2612781_DEL			5.21e-05
2R_1618770_SNP			5.26e-05
X_14993547_SNP	Rab3-GEF	INTRON	5.29e-05
2L_14087933_SNP	nAChRalpha5	INTRON	5.32e-05
2L_3013371_SNP	CG17265	INTRON	5.32e-05
X_18251495_SNP			5.38e-05
3L_10374559_INS			5.47e-05
3L_12404345_SNP	CG32103	INTRON	5.48e-05
2R_16825517_SNP	Rx	DOWNSTREAM	5.52e-05
2R_20260408_SNP	bs	INTRON	5.60e-05
3R_13421753_SNP	Sgs5	UTR_3_PRIME	5.63e-05
3R_13421753_SNP	CG7606	UTR_3_PRIME	5.63e-05
2L_2612787_SNP			5.66e-05
2R_3769346_SNP	Dgk	UTR_5_PRIME	5.66e-05
X_7587379_SNP	CHES-1-like	INTRON	5.67e-05
3L_13974741_SNP	CG17364	INTRON	5.74e-05
X_5908964_SNP	CR44499	DOWNSTREAM	5.74e-05
3R_12985703_SNP	Mur89F	INTRON	5.79e-05
X_14994112_SNP	Rab3-GEF	SYNONYMOUS_CODING	5.81e-05
2R_19645190_SNP	CG9850	INTRON	5.82e-05
X_9641716_SNP	Sp1	INTRON	5.85e-05
3R_3439387_SNP	CG34127	INTRON	5.86e-05
3R_12317562_SNP	Cad89D	INTRON	5.91e-05
3R_12317613_SNP	Cad89D	SYNONYMOUS_CODING	5.91e-05
X_9640876_SNP	Sp1	INTRON	5.92e-05
X_9640960_SNP	Sp1	INTRON	5.92e-05
2R_11632091_SNP	CG30089	INTRON	5.98e-05
3R_13332023_DEL	Dscam3	UPSTREAM	6.02e-05
3L_12544228_SNP	sowah	INTRON	6.04e-05
3R_10974468_SNP			6.10e-05
3R_19565035_SNP	Hmgcr	INTRON	6.10e-05
3R_19565036_SNP	Hmgcr	INTRON	6.10e-05
2R_20233630_SNP	bs	INTRON	6.16e-05
2R_19022154_SNP			6.27e-05
2R_20280846_SNP	slik	DOWNSTREAM	6.27e-05
3L_13935202_SNP	CG32137	INTRON	6.35e-05
X_9210165_SNP	CR44534	DOWNSTREAM	6.36e-05
2R_19551513_SNP	Pde8	INTRON	6.37e-05
X_6443825_SNP	CG34417	INTRON	6.44e-05
X_6444241_SNP	CG34417	INTRON	6.44e-05
X_6446431_SNP	CG34417	INTRON	6.44e-05
3L_18019988_SNP	Eip75B	INTRON	6.45e-05
3R_9949202_SNP	twf	SYNONYMOUS_CODING	6.45e-05
3R_9949202_SNP	140up	SYNONYMOUS_CODING	6.45e-05
2R_7402770_SNP			6.47e-05
3R_12985546_SNP	Mur89F	SYNONYMOUS_CODING	6.50e-05
X_3945990_SNP			6.50e-05
3R_17313053_SNP	CG7922	DOWNSTREAM	6.52e-05
3R_12992392_SNP	Mur89F	INTRON	6.53e-05
2R_11082631_SNP	CG43829	UPSTREAM	6.56e-05
X_4986299_SNP	rg	INTRON	6.56e-05
X_4986299_SNP	CG15465	INTRON	6.56e-05
2L_5613850_SNP	CG14010	INTRON	6.58e-05
2R_20276009_SNP	mAChR-A	INTRON	6.63e-05
3L_17773480_SNP			6.66e-05
3R_12992032_SNP	Mur89F	INTRON	6.69e-05
X_14518598_SNP	NetA	INTRON	6.73e-05
2L_14847382_SNP	CG15279	INTRON	6.75e-05
2R_7419910_SNP			6.80e-05
X_4986296_DEL	rg	INTRON	6.85e-05
X_4986296_DEL	CG15465	INTRON	6.85e-05
3R_10655781_SNP	btsz	INTRON	6.88e-05
2R_12696827_SNP			7.02e-05
2R_20263539_SNP	bs	UTR_3_PRIME	7.04e-05
3R_13928920_SNP	sr	INTRON	7.14e-05
2L_9962482_SNP	CG5850	SYNONYMOUS_CODING	7.15e-05
2L_9962482_SNP	CR43683	SYNONYMOUS_CODING	7.15e-05
2R_17103509_SNP	CG15661	SYNONYMOUS_CODING	7.15e-05
3R_17772582_SNP			7.17e-05
3R_12993769_SNP	Mur89F	INTRON	7.24e-05
4_214743_SNP	CG2316	UPSTREAM	7.30e-05
4_214743_SNP	CR44441	UPSTREAM	7.30e-05
X_14991195_SNP	Rab3-GEF	INTRON	7.35e-05
2R_7266548_SNP	Tsp47F	UTR_5_PRIME	7.37e-05
3R_19770553_SNP	CG12268	INTRON	7.39e-05
3L_13379241_SNP	CG10171	UTR_3_PRIME	7.40e-05
3L_13379241_SNP	CG14110	UTR_3_PRIME	7.40e-05
2L_4353069_SNP	CG15429	SYNONYMOUS_CODING	7.44e-05
2R_20276477_SNP	mAChR-A	INTRON	7.47e-05
2L_14858849_SNP			7.48e-05
X_3945994_SNP			7.48e-05
X_4883035_SNP	CR44833	INTRON	7.48e-05
2R_10963284_SNP			7.49e-05
2L_5684156_SNP			7.51e-05
2L_1611892_SNP	CG14352	INTRON	7.54e-05
2L_1611892_SNP	RFeSP	INTRON	7.54e-05
3R_3350035_SNP	alpha-Est6	DOWNSTREAM	7.54e-05
3R_3350035_SNP	alpha-Est7	DOWNSTREAM	7.54e-05
X_13400492_SNP	Neto	INTRON	7.54e-05
2R_20275800_SNP	mAChR-A	INTRON	7.55e-05
3R_22094885_SNP	CG6154	INTRON	7.57e-05
2R_9208823_SNP			7.61e-05
3L_14070418_SNP	btl	INTRON	7.63e-05
3R_12996262_SNP	Mur89F	INTRON	7.65e-05
3R_17309666_SNP	CG7922	INTRON	7.70e-05
3R_9755213_SNP			7.77e-05
2L_14839600_SNP	CR43805	DOWNSTREAM	7.85e-05
3L_13381805_SNP	Poc1	INTRON	7.88e-05
3L_13381805_SNP	CG10171	INTRON	7.88e-05
X_14993353_SNP	Rab3-GEF	INTRON	7.90e-05
X_13403437_SNP	Neto	INTRON	8.03e-05
2R_2589702_SNP	CG45092	INTRON	8.11e-05
2R_2589702_SNP	CG3409	INTRON	8.11e-05
2L_14839629_INS	CR43805	DOWNSTREAM	8.12e-05
3L_7002948_SNP	Mp	INTRON	8.12e-05
2R_20270526_SNP	mAChR-A	INTRON	8.25e-05
2L_5942852_SNP	Sfp26Ad	SYNONYMOUS_CODING	8.31e-05
2L_5942852_SNP	CR45289	SYNONYMOUS_CODING	8.31e-05
X_9641740_SNP	Sp1	INTRON	8.32e-05
2L_8590036_SNP	Sema-1a	INTRON	8.33e-05
2L_8590036_SNP	CR43855	INTRON	8.33e-05
3R_3453798_SNP	CG34127	INTRON	8.35e-05
3R_3453798_SNP	CR44332	INTRON	8.35e-05
4_216261_SNP	CR44441	EXON	8.38e-05
2L_3233946_SNP			8.43e-05
2L_8325829_SNP	CG7781	UPSTREAM	8.44e-05
3R_17307710_SNP	CG7922	UPSTREAM	8.47e-05
3L_6639868_SNP			8.62e-05
2R_19551586_SNP	Pde8	INTRON	8.63e-05
2L_3121567_SNP	toc	INTRON	8.68e-05
2L_5964588_SNP	psd	INTRON	8.69e-05
2L_5964588_SNP	CG13992	INTRON	8.69e-05
2L_6133846_SNP	CR45719	UPSTREAM	8.74e-05
2L_9810997_SNP	nAChRalpha6	INTRON	8.74e-05
2L_9811000_SNP	nAChRalpha6	INTRON	8.74e-05
3L_13383636_SNP	Poc1	UPSTREAM	8.77e-05
X_7585641_SNP	CHES-1-like	INTRON	8.81e-05
3R_17961180_SNP	SKIP	INTRON	8.88e-05
X_4533152_SNP	pon	DOWNSTREAM	8.92e-05
X_4533152_SNP	CG3081	DOWNSTREAM	8.92e-05
2R_16711423_SNP	insc	SYNONYMOUS_CODING	8.93e-05
2L_9962445_SNP	CG5850	INTRON	9.04e-05
2L_9962445_SNP	CR43683	INTRON	9.04e-05
X_14993974_SNP	Rab3-GEF	SYNONYMOUS_CODING	9.06e-05
3L_2293647_SNP	MsR2	INTRON	9.08e-05
3R_5916394_SNP	CR45054	DOWNSTREAM	9.08e-05
3R_5916394_SNP	mir-317	DOWNSTREAM	9.08e-05
3R_7317976_SNP			9.08e-05
3R_17313134_SNP	CG7922	DOWNSTREAM	9.11e-05
3R_5851098_SNP	Mical	INTRON	9.16e-05
3R_5851098_SNP	CG31407	INTRON	9.16e-05
2R_12835148_SNP	Vha16-4	DOWNSTREAM	9.17e-05
2R_12835148_SNP	CG34190	DOWNSTREAM	9.17e-05
3R_5285535_SNP	GstZ2	INTRON	9.18e-05
3R_9755225_SNP			9.19e-05
X_7585423_SNP	CHES-1-like	INTRON	9.23e-05
3R_13434002_SNP	sll	SYNONYMOUS_CODING	9.28e-05
3R_13434033_SNP	sll	UTR_3_PRIME	9.28e-05
2R_20257613_SNP	bs	INTRON	9.30e-05
2R_20257613_SNP	CR44811	INTRON	9.30e-05
2L_17966311_SNP	CG5674	INTRON	9.31e-05
2L_17966311_SNP	btv	INTRON	9.31e-05
3R_25873501_SNP	CG7943	SYNONYMOUS_CODING	9.31e-05
3R_25873501_SNP	CG15528	SYNONYMOUS_CODING	9.31e-05
2L_7751378_SNP	CG7203	DOWNSTREAM	9.33e-05
3R_20707017_SNP	CG11089	UTR_3_PRIME	9.35e-05
3R_20707017_SNP	CG31121	UTR_3_PRIME	9.35e-05
3R_7994186_SNP			9.36e-05
4_217807_DEL	CG31998	DOWNSTREAM	9.40e-05
X_4985793_MNP	rg	INTRON	9.40e-05
X_4985793_MNP	CG15465	INTRON	9.40e-05
2L_3427281_SNP	pgant2	UPSTREAM	9.43e-05
3L_12404239_SNP	CG32103	INTRON	9.45e-05
2R_3525595_SNP	CG43340	INTRON	9.47e-05
3R_5721722_SNP	Glut4EF	INTRON	9.56e-05
2R_11006133_SNP	chn	INTRON	9.60e-05
2L_16629322_SNP	CG42389	INTRON	9.61e-05
2L_16629322_SNP	CR44151	INTRON	9.61e-05
X_7585873_SNP	CHES-1-like	INTRON	9.63e-05
2R_3772313_SNP	Dgk	INTRON	9.68e-05
2L_7008310_SNP	uif	INTRON	9.69e-05
2L_14847378_SNP	CG15279	INTRON	9.70e-05
3R_12996121_SNP	Mur89F	INTRON	9.76e-05
2R_16875395_SNP	CG3216	SYNONYMOUS_CODING	9.77e-05
2R_20280640_SNP	slik	DOWNSTREAM	9.79e-05
3R_9585922_SNP	CG34383	INTRON	9.90e-05
3R_17313074_SNP	CG7922	DOWNSTREAM	9.93e-05
2L_14849398_SNP	CG15279	INTRON	9.95e-05
2L_2601212_SNP	CR44789	EXON	9.95e-05

6.5.2 Group count

grps	n
INTRON	217
DOWNSTREAM	43
SYNONYMOUS_CODING	40
UPSTREAM	19
NON_SYNONYMOUS_CODING	16
UTR_3_PRIME	15
UTR_5_PRIME	8
EXON	2

6.5.3 Gene counts

gene	n
prom	23
Mur89F	19
bs	11
CG7922	11
Rab3-GEF	9
Sp1	8
CG7203	6
CHES-1-like	6
BBS4	5
CG15465	5
CG45068	5
CG45069	5
mAChR-A	5
rg	5
CG12268	4
CG15279	4
CG6106	4
Cad89D	3
CG15876	3
CG34417	3
CG6154	3
Hmgcr	3
MsR2	3
nAChRalpha6	3
RhoGEF64C	3
140up	2
btsz	2
CG10171	2
CG12006	2
CG13992	2
CG14352	2
CG15661	2
CG18519	2
CG2316	2
CG32103	2
CG34127	2
CG42531	2
CG43829	2
CG5850	2
CR43683	2
CR43805	2
CR44441	2
CR44792	2
CR44811	2
Damm	2
Dgk	2
Dscam3	2
EcR	2
IntS6	2
Lgr1	2
Mp	2
Neto	2
Ntf-2	2
nuf	2
p	2
Pde8	2
Poc1	2
psd	2
RFeSP	2
Rx	2
slik	2
sll	2
twf	2
AdamTS-A	1
Ald	1
alpha-Est6	1
alpha-Est7	1
bel	1
btl	1
btv	1
capu	1
CG10804	1
CG10960	1
CG11073	1
CG11089	1
CG13123	1
CG1339	1
CG13739	1
CG13954	1
CG14010	1
CG14110	1
CG14285	1
CG14286	1
CG14323	1
CG14961	1
CG15394	1
CG15395	1
CG15429	1
CG15528	1
CG15742	1
CG17265	1
CG17364	1
CG2065	1
CG2070	1
CG2556	1
CG30089	1
CG30389	1
CG30495	1
CG3081	1
CG31121	1
CG31407	1
CG31998	1
CG32137	1
CG32141	1
CG3216	1
CG32758	1
CG33275	1
CG33298	1
CG3409	1
CG34190	1
CG34295	1
CG34383	1
CG42383	1
CG42389	1
CG43340	1
CG44434	1
CG44435	1
CG45086	1
CG45092	1
CG45263	1
CG5359	1
CG5361	1
CG5674	1
CG7587	1
CG7606	1
CG7781	1
CG7943	1
CG7997	1
CG8177	1
CG9850	1
chn	1
CR32773	1
CR43669	1
CR43804	1
CR43855	1
CR44151	1
CR44332	1
CR44499	1
CR44534	1
CR44789	1
CR44833	1
CR44999	1
CR45054	1
CR45289	1
CR45380	1
CR45719	1
DAT	1
Eip75B	1
erm	1
esn	1
Galphaq	1
Glut4EF	1
grp	1
GstZ2	1
ham	1
insc	1
intr	1
MAPk-Ak2	1
mew	1
Mical	1
mir-317	1
msl-2	1
nAChRalpha5	1
NetA	1
NPF	1
Obp85a	1
osa	1
Pdsw	1
pgant2	1
pon	1
rad	1
rau	1
sbb	1
Sema-1a	1
Sfp26Ad	1
Sgs5	1
SKIP	1
sowah	1
Spn85F	1
sr	1
Tm1	1
toc	1
trio	1
tRNA:CR33534	1
Tsp47F	1
uif	1
Vha16-4	1
Vha44	1

7 Phenotypes

7.1 Figure 1

7.2 Figure 1 (with the scatter plot)

7.3 Thermal Breadth Correlation

8 Manhattan plots

9 Transription factors

9.1 DEG

deg	TFs	Up-regulated	Down-regulated
Cold	321	109	212
Hot	386	142	244

9.1.1 Heat-shock

gene	log2FoldChange	padj
Plzf	1.467	6.28e-05
CG12071	1.435	6.862e-07
bcd	1.247	1.122e-10
hb	1.191	1.485e-08
insv	1.053	2.68e-09
phol	1.028	8.707e-22
jumu	1.003	5.147e-10
mod(mdg4)	0.9869	8.727e-16
tef	0.9769	1.153e-06
ovo	0.9665	9.264e-15
CG31224	0.9654	1.141e-15
retn	0.964	5.074e-09
woc	0.9423	1.623e-15
E2f2	0.9336	6.871e-06
Clamp	0.9166	6.447e-08
cad	0.9145	7.417e-11
CG8944	0.9068	9.797e-09
Hsf	0.9051	4.555e-10
CG8924	0.9044	1.468e-05
CG10321	0.9011	1.159e-14
CG17361	0.8891	1.185e-05
hang	0.8853	1.298e-13
pad	0.882	2.002e-07
wdn	0.8669	4.07e-08
GATAd	0.8652	1.936e-07
da	0.8578	2.725e-20
Aef1	0.8546	3.763e-12
Nf-YA	0.8519	3.214e-07
CG12104	0.8468	1.416e-05
CG4282	0.8431	2.328e-05
CG4936	0.8373	1.991e-05
CG31365	0.835	3.523e-05
pita	0.8347	1.573e-08
MESR4	0.8325	1.323e-14
E(bx)	0.8302	8.809e-10
chn	0.83	6.909e-09
pzg	0.8293	9.677e-12
Nf-YC	0.8285	6.157e-09
CG12391	0.8272	4.309e-08
CG8478	0.8213	0.002643
zf30C	0.8111	4.773e-08
BtbVII	0.8025	6.538e-11
D19A	0.7993	3.586e-07
NC2alpha	0.7946	0.003736
Cp190	0.7882	1.76e-11
apt	0.7864	2.138e-09
Stat92E	0.7815	2.575e-08
Br140	0.7793	4.458e-08
CG12659	0.7766	0.003406
usp	0.7706	7.054e-07
CG14965	0.7691	0.00204
polybromo	0.7686	4.48e-07
mld	0.7677	6.187e-08
CG12219	0.7615	0.001582
lola	0.7576	8.36e-12
Adf1	0.7349	6.965e-05
CG12299	0.73	0.0003555
psq	0.7276	4.136e-11
CG3847	0.7235	3.74e-10
Xbp1	0.7164	1.148e-05
tgo	0.7161	1.33e-07
CG10959	0.7029	0.007737
Cf2	0.7015	6.887e-09
exd	0.7009	1.544e-06
sima	0.7001	1.77e-08
cic	0.6936	5.673e-11
CTCF	0.6927	2.307e-05
CG30020	0.6926	0.0003136
z	0.6925	6.072e-08
cyc	0.6819	0.0001915
CG2199	0.6786	8.027e-08
D1	0.6767	4.94e-18
dl	0.6718	3.711e-08
su(Hw)	0.6701	0.000255
ken	0.6681	1.551e-05
Ssrp	0.6645	4.002e-07
CG9932	0.6632	0.001238
jing	0.6606	2.288e-09
Mrtf	0.6591	6.975e-13
MTA1-like	0.6552	4.198e-08
CG32767	0.6519	6.401e-08
Dp	0.6477	1.874e-08
Spps	0.6446	6.639e-07
az2	0.6361	0.006841
HmgD	0.6345	6.187e-08
CG12942	0.6314	6.631e-06
ssp	0.6307	6.112e-05
lilli	0.6262	2.893e-06
CG12236	0.6203	3.705e-06
Med	0.6202	6.823e-05
dbr	0.6176	0.001656
CG15435	0.6162	0.003805
Mad	0.6156	9.6e-07
cg	0.615	7.621e-11
pho	0.6132	0.002743
CG7987	0.6018	0.0001528
MBD-R2	0.6002	6.532e-06
Myb	0.5992	0.000199
Deaf1	0.5989	8.406e-10
Usf	0.5938	0.0005912
CG4360	0.5871	3.73e-07
cnc	0.5858	1.364e-06
Mitf	0.585	0.002795
Eip75B	0.5849	0.0004795
CG11247	0.5845	0.0002502
Meics	0.5843	0.001253
aop	0.5841	2.166e-05
CG10979	0.5803	0.0004165
ftz-f1	0.578	4.616e-07
CG2202	0.5738	0.006926
Hr96	0.5725	9.933e-05
CG10631	0.571	0.000357
Dref	0.5435	6.007e-05
CG15514	0.5358	0.004192
CG10462	0.535	0.001385
CG3065	0.5317	0.0001808
fs(1)h	0.5311	4.986e-05
CG9609	0.5273	0.001084
CG2116	0.5123	0.007626
sqz	0.4958	0.009534
CG10543	0.4949	2.542e-06
CG17829	0.4934	0.001356
Su(H)	0.4919	0.001289
CG32772	0.4842	0.0001428
Glut4EF	0.4774	0.002004
CG12054	0.4676	0.000726
stc	0.4459	0.001811
Mnt	0.44	0.001815
tai	0.4387	0.002338
CG6791	0.434	0.004502
row	0.4216	0.005631
bun	0.4166	0.000527
Smox	0.4083	0.003182
TFAM	0.399	0.002788
CG17385	0.3948	0.001653
CG11970	0.3909	0.007217
ttk	0.3764	0.0005769
crp	0.373	0.0005034
M1BP	0.3715	0.004144
crol	0.3647	0.005616
EcR	0.3606	0.005235
NFAT	0.3528	0.0006447
Ubx	-0.5263	0.007598
zfh2	-0.5631	7.69e-05
CG31612	-0.6856	0.00354
HmgZ	-0.6862	0.0001288
vnd	-0.7212	0.0067
abd-A	-0.7478	0.002395
vvl	-0.7504	0.007795
bowl	-0.7507	0.003517
fru	-0.7624	0.0002635
chinmo	-0.7729	9.461e-05
tsh	-0.7791	0.0003196
dve	-0.7935	9.027e-05
Sox102F	-0.817	0.001398
Hr38	-0.8253	0.006285
Kah	-0.8757	0.003915
mirr	-0.8773	0.0001026
sens-2	-0.8845	0.0009101
sr	-0.8971	0.0008828
fkh	-0.8998	4.686e-06
ap	-0.9056	0.0006074
fuss	-0.9281	0.004046
knrl	-0.9463	0.00428
pdm3	-0.9607	5.231e-06
CG12605	-0.9641	0.0001113
Six4	-0.9651	0.0001184
CG4496	-0.9686	0.0005481
CG32121	-0.976	0.007424
CG16779	-1.017	1.585e-06
onecut	-1.026	0.0001666
Ptx1	-1.03	2.222e-05
salm	-1.059	0.0004024
disco-r	-1.08	0.0002355
SoxN	-1.097	0.0002635
tio	-1.136	0.000466
Dll	-1.2	6.167e-05
grh	-1.205	2.98e-13
CG11617	-1.207	0.001218
svp	-1.213	1.228e-07
CG6808	-1.247	0.001066
sug	-1.26	4.539e-05
bi	-1.281	1.48e-05
Sp1	-1.301	1.598e-05
Dr	-1.311	0.0001905
Ets98B	-1.339	7.783e-08
disco	-1.347	2.725e-06
Lim1	-1.349	0.0003582
Antp	-1.402	1.445e-10
ab	-1.417	9.789e-11
CG14655	-1.46	0.004175
CG43347	-1.464	5.292e-09
CG16863	-1.507	0.0002512
oc	-1.511	2.487e-05
dar1	-1.515	2.262e-05
so	-1.521	1.549e-07
CG13775	-1.526	0.0007966
CG17803	-1.565	0.008424
mid	-1.585	5.061e-10
CG6813	-1.585	0.0001325
toy	-1.611	5.318e-07
Eip78C	-1.651	2.524e-08
lab	-1.675	0.001636
esg	-1.715	0.002406
GATAe	-1.716	1.168e-09
nub	-1.736	5.008e-10
org-1	-1.755	6.68e-07
CG10348	-1.766	3.875e-05
CG6765	-1.776	0.0001325
caup	-1.778	7.008e-10
CG17801	-1.804	0.004766
Sox100B	-1.863	0.001091
trh	-1.871	1.677e-11
odd	-1.895	1.168e-09
CG2120	-1.941	1.046e-05
ham	-1.956	2.107e-11
Abd-B	-1.984	8.306e-10
CG14050	-1.991	0.002962
kni	-2.038	6.855e-10
dac	-2.043	5.901e-11
opa	-2.051	0.000724
FoxP	-2.056	7.736e-07
H15	-2.063	5.301e-11
toe	-2.069	1.498e-06
tup	-2.108	6.612e-09
CG14860	-2.109	0.0006494
gl	-2.127	1.041e-06
rn	-2.14	2.085e-08
Ets21C	-2.199	1.957e-11
Doc1	-2.204	0.0002914
Scr	-2.21	1.028e-06
Sox21b	-2.237	3.348e-06
B-H1	-2.259	0.001562
sv	-2.277	1.693e-13
Awh	-2.278	0.001685
Lim3	-2.279	8e-07
B-H2	-2.358	9.88e-08
slp1	-2.364	0.003897
dpn	-2.379	0.001909
acj6	-2.401	9.592e-08
topi	-2.432	0.000195
CG4374	-2.437	5.686e-08
Sox15	-2.444	3.242e-06
eve	-2.451	0.003517
slp2	-2.515	1.762e-06
nau	-2.52	1.174e-07
E(spl)m7-HLH	-2.555	0.008501
ss	-2.56	1.883e-09
lov	-2.584	0.0003596
byn	-2.586	3.462e-06
CG18265	-2.592	5.254e-13
grn	-2.608	4.334e-08
CG7368	-2.613	1.772e-06
unc-4	-2.618	2.561e-07
CG42741	-2.622	0.0004295
D	-2.63	2.369e-07
btd	-2.632	1.418e-05
cas	-2.651	2.93e-09
rib	-2.71	0.002472
repo	-2.761	4.53e-09
pnr	-2.803	5.955e-10
kn	-2.809	1.305e-10
ey	-2.835	1.119e-08
Poxm	-2.853	2.334e-08
ara	-2.856	1.174e-07
lz	-2.862	1.544e-10
pdm2	-2.876	1.03e-10
fd96Cb	-2.891	0.007248
Sox21a	-2.897	1.978e-06
Kr	-2.9	0.0001165
sob	-2.919	8.528e-07
dan	-2.926	0.001798
CG32532	-2.93	3.805e-07
net	-2.933	1.524e-10
E5	-2.964	1.119e-07
CG34031	-2.99	0.006284
zen	-2.991	5.262e-05
Crg-1	-3.003	4.499e-05
salr	-3.028	4.671e-17
Dfd	-3.039	6.296e-09
TfAP-2	-3.069	2.392e-06
run	-3.076	3.035e-05
Ets65A	-3.076	1.027e-07
Pph13	-3.077	7.009e-06
otp	-3.114	1.355e-10
slou	-3.15	0.003981
bab1	-3.158	1.797e-14
dmrt99B	-3.195	5.766e-05
CG4328	-3.226	0.003283
lbl	-3.235	1.488e-07
Fer1	-3.24	5.75e-05
Optix	-3.261	2.207e-06
CG13894	-3.265	2.542e-06
croc	-3.314	1.067e-06
CG32006	-3.315	5.884e-07
twi	-3.375	5.999e-08
en	-3.42	1.078e-06
eyg	-3.432	7.525e-10
bap	-3.455	1.907e-06
H2.0	-3.482	5.107e-06
danr	-3.506	4.084e-09
RunxA	-3.511	9.743e-10
Dbx	-3.536	7.49e-05
sens	-3.557	0.001085
inv	-3.638	4.794e-06
tap	-3.645	3.36e-06
hbn	-3.659	2.205e-05
eg	-3.66	1.169e-05
Doc3	-3.668	0.0006998
nerfin-1	-3.724	9.763e-05
bin	-3.733	4.945e-09
Ets96B	-3.744	4.109e-11
CG13287	-3.776	4.42e-05
Oli	-3.779	1.873e-06
E(spl)m8-HLH	-3.836	0.003942
Vsx2	-3.892	7.133e-08
fd102C	-3.942	9.7e-07
HGTX	-3.95	3.09e-10
unpg	-3.977	0.0001238
E(spl)mdelta-HLH	-3.98	9.769e-06
pb	-3.985	1.906e-09
vis	-4.029	0.001343
dmrt93B	-4.042	3.616e-05
CG11294	-4.067	2.281e-06
C15	-4.09	6.544e-05
HHEX	-4.129	4.776e-05
lmd	-4.166	5.506e-09
gcm	-4.189	0.008687
Oaz	-4.194	5.324e-07
CG7786	-4.24	0.0003943
Vsx1	-4.289	2.671e-08
erm	-4.316	2.629e-14
lms	-4.385	5.593e-08
al	-4.443	1.78e-08
fd59A	-4.45	3.584e-05
dmrt11E	-4.497	7.111e-06
Gsc	-4.517	0.001468
PHDP	-4.571	0.0009058
Hmx	-4.581	1.432e-12
Fer2	-4.599	0.0001236
ro	-4.643	0.004167
Hr83	-4.697	0.0008417
RunxB	-4.697	4.654e-06
dimm	-4.761	1.172e-05
gsb	-4.773	0.0001232
tin	-4.781	4.194e-06
ase	-4.794	8.666e-09
sc	-4.838	4.071e-06
lbe	-4.843	7.033e-08
Hey	-4.871	3.807e-07
CG18599	-5.002	3.459e-05
gsb-n	-5.033	3.182e-08
Poxn	-5.075	4.61e-13
CG15696	-5.13	0.004168
HLH4C	-5.194	8.768e-05
Rx	-5.404	4.611e-10
dsf	-5.454	2.229e-06
bsh	-5.553	8.916e-07
CG15269	-5.57	0.0006733
Hr51	-5.668	6.751e-10
hkb	-5.798	2.572e-09
HLH3B	-5.823	6.649e-07
OdsH	-5.847	8.882e-07
gcm2	-6.001	0.0002684
CG4318	-6.019	4.296e-06
ftz	-6.318	5.815e-06
fd19B	-6.441	4.602e-05
CG34367	-6.736	1.159e-07
fd3F	-6.818	1.731e-07
amos	-6.999	7.164e-05
Neu2	-7.156	2.167e-07
fd96Ca	-7.373	7.423e-09
tll	-7.403	2.798e-08
prd	-7.669	3.684e-12
term	-7.726	1.861e-05
zen2	-7.804	5.121e-05
Fer3	-7.884	0.0001366
ac	-8.116	1.286e-05
CG11085	-8.133	1.688e-07
CG7963	-8.415	7.364e-08
wor	-8.461	1.212e-08
CG15710	-8.651	1.784e-06
CG7691	-8.804	1.182e-07
sisA	-8.815	7.669e-06
nerfin-2	-8.876	1.435e-10
CG13617	-10.11	3.71e-09

9.1.2 Cold-shock

gene	log2FoldChange	padj
srp	1.028	3.134e-10
insv	0.9137	5.317e-07
hb	0.8772	5.015e-05
CG17361	0.8353	6.672e-05
phol	0.8291	9.254e-14
CG9609	0.7717	3.331e-06
tgo	0.7714	3.223e-08
retn	0.7688	5.833e-06
cad	0.7568	1.63e-07
Cp190	0.7547	3.322e-10
vri	0.7535	0.0006789
HmgD	0.7502	3.986e-10
bcd	0.7454	0.000187
Ssrp	0.7398	3.978e-08
woc	0.7379	1.521e-09
hang	0.7378	2.044e-09
apt	0.736	4.878e-08
Clamp	0.7256	3.283e-05
pita	0.7201	2.299e-06
E(bx)	0.7074	3.763e-07
CG4936	0.7031	0.0005188
MESR4	0.6917	5.21e-10
mod(mdg4)	0.6904	5.491e-08
jumu	0.6901	3.372e-05
chn	0.6874	3.126e-06
D1	0.684	1.687e-17
GATAd	0.6725	8.685e-05
CG12391	0.6701	1.688e-05
CG8924	0.67	0.001808
CG8944	0.6695	3.943e-05
pzg	0.6693	9.483e-08
usp	0.6691	2.954e-05
Nf-YC	0.6654	5.948e-06
CG12219	0.6645	0.007459
CG3065	0.6616	6.24e-06
CG31224	0.6606	1.2e-07
su(Hw)	0.6579	0.0004856
pad	0.6565	0.0001757
Spps	0.6545	9.739e-07
da	0.6498	1.814e-11
CTCF	0.6482	0.0001192
CG12942	0.6254	1.535e-05
sima	0.6211	1.161e-06
Sox14	0.6184	0.00181
Aef1	0.6164	1.181e-06
bun	0.6157	6.258e-07
Mnt	0.6061	2.945e-05
Rel	0.6056	0.004253
CG31365	0.6046	0.003656
BtbVII	0.6013	2.061e-06
cg	0.5983	6.623e-10
tef	0.5982	0.003859
mld	0.5952	4.548e-05
CG2202	0.5937	0.006495
cic	0.5926	5.2e-08
CG12299	0.5912	0.004952
CG2199	0.5909	5.833e-06
MTA1-like	0.5907	1.587e-06
ken	0.5903	0.0002091
CG32767	0.584	2.498e-06
CG10979	0.5828	0.0005742
aop	0.5787	4.353e-05
CG12236	0.5772	2.955e-05
ovo	0.576	8.284e-06
lola	0.5741	4.847e-07
pho	0.5706	0.006642
psq	0.5692	5.29e-07
z	0.5688	1.719e-05
CG4282	0.5643	0.006023
Nf-YA	0.5605	0.001167
CG4360	0.5542	3.281e-06
Hsf	0.5455	0.0002677
Mad	0.5453	2.598e-05
Mrtf	0.5345	1.76e-08
wdn	0.5272	0.001208
D19A	0.5225	0.00128
Dp	0.5208	1.157e-05
CG10321	0.5149	2.396e-05
cyc	0.5133	0.00651
zf30C	0.5117	0.0008523
CG12054	0.5106	0.0003316
Su(H)	0.5099	0.001193
ssp	0.5067	0.001831
lilli	0.5002	0.0002809
CG3847	0.4992	3.059e-05
stc	0.4891	0.0008705
CG10543	0.4877	6.778e-06
ftz-f1	0.4876	3.612e-05
crol	0.487	0.0003144
fs(1)h	0.4857	0.0003085
Stat92E	0.4841	0.0007987
polybromo	0.4812	0.002155
Cf2	0.4581	0.0002381
dl	0.4567	0.0002808
Deaf1	0.4506	8.285e-06
exd	0.4482	0.002864
Br140	0.4461	0.002367
Myb	0.441	0.007866
jing	0.4395	0.0001163
Dref	0.437	0.001766
CG32772	0.4274	0.001128
TFAM	0.4208	0.002237
Hr96	0.4091	0.007038
MBD-R2	0.4061	0.00314
Dsp1	0.3712	0.005967
M1BP	0.3543	0.008075
CG17385	0.3513	0.006499
crp	0.3446	0.001792
ttk	0.3126	0.005435
Eip74EF	-0.3976	0.006202
zfh2	-0.444	0.002474
Rfx	-0.5994	0.006591
CG12605	-0.6778	0.008081
CG31612	-0.6899	0.004598
tsh	-0.7613	0.0006817
Dll	-0.8284	0.006951
chinmo	-0.8518	3.153e-05
CG4496	-0.8523	0.003231
H15	-0.8617	0.00583
grh	-0.8753	2.758e-07
pdm3	-0.8772	5.914e-05
CG12071	-0.8989	0.003288
Hr38	-0.9228	0.003039
kni	-0.9262	0.005147
fuss	-0.9475	0.004403
CG16779	-0.9538	1.25e-05
Antp	-1.021	5.415e-06
org-1	-1.062	0.0031
caup	-1.145	9.593e-05
ab	-1.173	1.985e-07
ham	-1.19	6.239e-05
Eip78C	-1.205	7.055e-05
disco-r	-1.219	5.982e-05
toy	-1.222	0.0002064
CG43347	-1.241	1.515e-06
bi	-1.256	3.931e-05
oc	-1.3	0.0004242
Lim1	-1.325	0.000685
so	-1.34	7.877e-06
onecut	-1.354	1.767e-06
net	-1.376	0.002133
CG6808	-1.437	0.0003117
tio	-1.455	1.794e-05
pdm2	-1.485	0.0008209
CG16863	-1.485	0.0005193
tx	-1.529	0.001829
Ets21C	-1.534	4.362e-06
E(spl)m3-HLH	-1.543	1.764e-05
CG6765	-1.547	0.001204
Abd-B	-1.574	1.998e-06
dac	-1.611	4.713e-07
unc-4	-1.644	0.001343
tup	-1.652	9.081e-06
Sox21b	-1.679	0.0006362
CG17803	-1.686	0.006033
CG6813	-1.695	0.0001019
rn	-1.716	1.149e-05
Lim3	-1.721	0.000264
ems	-1.728	0.002555
CG17801	-1.736	0.008434
toe	-1.788	5.502e-05
slp2	-1.802	0.000729
gl	-1.803	5.61e-05
opa	-1.821	0.003525
btd	-1.822	0.003055
CG13775	-1.825	0.0001454
CG14860	-1.896	0.002909
kn	-1.918	1.434e-05
byn	-1.982	0.0004888
D	-1.982	0.0001305
sv	-2.004	2.945e-10
gt	-2.031	0.0001503
acj6	-2.061	8.422e-06
CG7368	-2.07	0.0002081
salr	-2.078	1.279e-08
Dfd	-2.088	6.894e-05
ss	-2.137	9.78e-07
trh	-2.138	2.011e-13
CG4374	-2.145	3.363e-06
Scr	-2.155	4.091e-06
nau	-2.189	9.132e-06
CG18265	-2.196	2.474e-09
CG10348	-2.242	6.979e-07
zen	-2.293	0.002232
Fer1	-2.298	0.004616
en	-2.314	0.0009984
H2.0	-2.318	0.002352
pnr	-2.34	4.41e-07
sob	-2.347	0.000105
lov	-2.373	0.001431
Sox15	-2.391	1.113e-05
Awh	-2.403	0.001382
topi	-2.438	0.0003181
ara	-2.449	9.63e-06
B-H2	-2.47	9.041e-08
TfAP-2	-2.479	0.0001871
grn	-2.48	4.624e-07
B-H1	-2.48	0.0008523
CG32532	-2.518	2.102e-05
rib	-2.523	0.00603
Poxm	-2.533	1.402e-06
dpn	-2.534	0.001428
Pph13	-2.538	0.0002816
ey	-2.576	4.543e-07
sc	-2.578	0.008095
twi	-2.583	3.854e-05
Doc1	-2.592	5.899e-05
E5	-2.601	5.811e-06
hbn	-2.608	0.002512
CG32006	-2.679	7.239e-05
bap	-2.693	0.0002431
bab1	-2.701	1.577e-10
eyg	-2.714	1.538e-06
Vsx2	-2.718	0.0001488
Oli	-2.738	0.0005134
fd102C	-2.758	0.0005627
tap	-2.831	0.0003334
FoxP	-2.831	1.577e-10
CG42741	-2.832	0.000255
erm	-2.86	1.846e-07
bin	-2.892	6.683e-06
croc	-2.937	2.801e-05
lbl	-2.939	3.662e-06
unpg	-2.987	0.004162
HLH54F	-2.988	0.005604
CG13287	-3.054	0.001116
Optix	-3.062	1.716e-05
cas	-3.076	1.363e-10
danr	-3.116	4.303e-07
lbe	-3.123	0.0003163
lz	-3.154	3.081e-11
RunxA	-3.203	5.657e-08
run	-3.211	3.167e-05
bsh	-3.22	0.002765
slou	-3.222	0.004281
otp	-3.355	7.126e-11
CG11085	-3.355	0.002285
CG11294	-3.388	0.0001033
Ets96B	-3.397	6.011e-09
CG4328	-3.398	0.002893
eg	-3.402	7.955e-05
Oaz	-3.417	5.723e-05
fd59A	-3.46	0.001314
Ets65A	-3.475	9.709e-09
CG13617	-3.504	0.003781
CG13894	-3.545	1.457e-06
Hmx	-3.549	3.259e-08
Rx	-3.585	1.86e-05
pb	-3.619	1.042e-07
al	-3.658	4.271e-06
C15	-3.81	0.0003086
dan	-3.81	0.0001076
Doc3	-3.813	0.0007004
dimm	-3.869	0.0004282
eve	-3.871	5.203e-05
Dbx	-3.902	4.473e-05
hkb	-3.91	1.061e-05
Vsx1	-3.917	7.812e-07
CG34367	-3.945	0.000375
nerfin-1	-3.946	7.675e-05
E(spl)m7-HLH	-3.962	0.0002569
HGTX	-4.011	1.473e-09
CG7963	-4.012	0.0002494
lms	-4.045	1.349e-06
prd	-4.105	1.403e-07
sna	-4.141	0.002998
fd19B	-4.143	0.003655
dmrt99B	-4.17	2.29e-06
Gsc	-4.226	0.00374
RunxB	-4.242	5.402e-05
sisA	-4.243	0.009601
Poxn	-4.249	1.46e-09
PHDP	-4.262	0.002717
gsb	-4.355	0.000652
CG9876	-4.356	0.006096
wor	-4.367	1.755e-05
nerfin-2	-4.371	1.144e-07
ase	-4.427	3.188e-07
term	-4.46	0.004252
inv	-4.466	1.006e-07
HHEX	-4.475	4.21e-05
E(spl)mgamma-HLH	-4.51	0.001086
Neu2	-4.528	8.867e-05
E(spl)m8-HLH	-4.537	0.002061
CG18599	-4.631	0.0002061
Doc2	-4.659	0.0006841
HLH4C	-4.662	0.0005663
gcm	-4.739	0.00458
dsf	-4.771	4.529e-05
CG33557	-4.872	0.006958
lmd	-4.965	4.591e-10
CG7691	-4.973	0.000133
E(spl)m5-HLH	-4.976	0.006159
Hr51	-4.98	8.417e-08
gsb-n	-4.99	2.705e-07
CG4318	-5.132	8.379e-05
Kr	-5.151	2.654e-09
gcm2	-5.176	0.001807
HLH3B	-5.21	1.437e-05
Hey	-5.231	1.378e-06
tll	-5.26	7.865e-06
Hr83	-5.29	0.0007808
tin	-5.36	3.286e-06
fd96Cb	-5.511	5.402e-05
ftz	-5.6	9.431e-05
Fer2	-5.706	2.841e-05
OdsH	-5.938	1.055e-05
ro	-6.017	0.001023
CG15710	-6.048	0.0003508
dmrt93B	-6.117	2.365e-06
zen2	-6.297	0.001434
CG7786	-6.432	0.0001347
dmrt11E	-6.528	1.46e-06
CG34031	-6.586	8.336e-05
E(spl)mdelta-HLH	-6.624	1.951e-06
CG15696	-7.248	0.0005221
Fer3	-7.342	0.0005514
CG15336	-7.427	0.001094
cato	-7.578	0.0006299
fd3F	-7.829	2.746e-06
fd96Ca	-8.983	2.222e-08

9.1.3 Cold-shock

gene	log2FoldChange	padj
srp	1.028	3.134e-10
insv	0.9137	5.317e-07
hb	0.8772	5.015e-05
CG17361	0.8353	6.672e-05
phol	0.8291	9.254e-14
CG9609	0.7717	3.331e-06
tgo	0.7714	3.223e-08
retn	0.7688	5.833e-06
cad	0.7568	1.63e-07
Cp190	0.7547	3.322e-10
vri	0.7535	0.0006789
HmgD	0.7502	3.986e-10
bcd	0.7454	0.000187
Ssrp	0.7398	3.978e-08
woc	0.7379	1.521e-09
hang	0.7378	2.044e-09
apt	0.736	4.878e-08
Clamp	0.7256	3.283e-05
pita	0.7201	2.299e-06
E(bx)	0.7074	3.763e-07
CG4936	0.7031	0.0005188
MESR4	0.6917	5.21e-10
mod(mdg4)	0.6904	5.491e-08
jumu	0.6901	3.372e-05
chn	0.6874	3.126e-06
D1	0.684	1.687e-17
GATAd	0.6725	8.685e-05
CG12391	0.6701	1.688e-05
CG8924	0.67	0.001808
CG8944	0.6695	3.943e-05
pzg	0.6693	9.483e-08
usp	0.6691	2.954e-05
Nf-YC	0.6654	5.948e-06
CG12219	0.6645	0.007459
CG3065	0.6616	6.24e-06
CG31224	0.6606	1.2e-07
su(Hw)	0.6579	0.0004856
pad	0.6565	0.0001757
Spps	0.6545	9.739e-07
da	0.6498	1.814e-11
CTCF	0.6482	0.0001192
CG12942	0.6254	1.535e-05
sima	0.6211	1.161e-06
Sox14	0.6184	0.00181
Aef1	0.6164	1.181e-06
bun	0.6157	6.258e-07
Mnt	0.6061	2.945e-05
Rel	0.6056	0.004253
CG31365	0.6046	0.003656
BtbVII	0.6013	2.061e-06
cg	0.5983	6.623e-10
tef	0.5982	0.003859
mld	0.5952	4.548e-05
CG2202	0.5937	0.006495
cic	0.5926	5.2e-08
CG12299	0.5912	0.004952
CG2199	0.5909	5.833e-06
MTA1-like	0.5907	1.587e-06
ken	0.5903	0.0002091
CG32767	0.584	2.498e-06
CG10979	0.5828	0.0005742
aop	0.5787	4.353e-05
CG12236	0.5772	2.955e-05
ovo	0.576	8.284e-06
lola	0.5741	4.847e-07
pho	0.5706	0.006642
psq	0.5692	5.29e-07
z	0.5688	1.719e-05
CG4282	0.5643	0.006023
Nf-YA	0.5605	0.001167
CG4360	0.5542	3.281e-06
Hsf	0.5455	0.0002677
Mad	0.5453	2.598e-05
Mrtf	0.5345	1.76e-08
wdn	0.5272	0.001208
D19A	0.5225	0.00128
Dp	0.5208	1.157e-05
CG10321	0.5149	2.396e-05
cyc	0.5133	0.00651
zf30C	0.5117	0.0008523
CG12054	0.5106	0.0003316
Su(H)	0.5099	0.001193
ssp	0.5067	0.001831
lilli	0.5002	0.0002809
CG3847	0.4992	3.059e-05
stc	0.4891	0.0008705
CG10543	0.4877	6.778e-06
ftz-f1	0.4876	3.612e-05
crol	0.487	0.0003144
fs(1)h	0.4857	0.0003085
Stat92E	0.4841	0.0007987
polybromo	0.4812	0.002155
Cf2	0.4581	0.0002381
dl	0.4567	0.0002808
Deaf1	0.4506	8.285e-06
exd	0.4482	0.002864
Br140	0.4461	0.002367
Myb	0.441	0.007866
jing	0.4395	0.0001163
Dref	0.437	0.001766
CG32772	0.4274	0.001128
TFAM	0.4208	0.002237
Hr96	0.4091	0.007038
MBD-R2	0.4061	0.00314
Dsp1	0.3712	0.005967
M1BP	0.3543	0.008075
CG17385	0.3513	0.006499
crp	0.3446	0.001792
ttk	0.3126	0.005435
Eip74EF	-0.3976	0.006202
zfh2	-0.444	0.002474
Rfx	-0.5994	0.006591
CG12605	-0.6778	0.008081
CG31612	-0.6899	0.004598
tsh	-0.7613	0.0006817
Dll	-0.8284	0.006951
chinmo	-0.8518	3.153e-05
CG4496	-0.8523	0.003231
H15	-0.8617	0.00583
grh	-0.8753	2.758e-07
pdm3	-0.8772	5.914e-05
CG12071	-0.8989	0.003288
Hr38	-0.9228	0.003039
kni	-0.9262	0.005147
fuss	-0.9475	0.004403
CG16779	-0.9538	1.25e-05
Antp	-1.021	5.415e-06
org-1	-1.062	0.0031
caup	-1.145	9.593e-05
ab	-1.173	1.985e-07
ham	-1.19	6.239e-05
Eip78C	-1.205	7.055e-05
disco-r	-1.219	5.982e-05
toy	-1.222	0.0002064
CG43347	-1.241	1.515e-06
bi	-1.256	3.931e-05
oc	-1.3	0.0004242
Lim1	-1.325	0.000685
so	-1.34	7.877e-06
onecut	-1.354	1.767e-06
net	-1.376	0.002133
CG6808	-1.437	0.0003117
tio	-1.455	1.794e-05
pdm2	-1.485	0.0008209
CG16863	-1.485	0.0005193
tx	-1.529	0.001829
Ets21C	-1.534	4.362e-06
E(spl)m3-HLH	-1.543	1.764e-05
CG6765	-1.547	0.001204
Abd-B	-1.574	1.998e-06
dac	-1.611	4.713e-07
unc-4	-1.644	0.001343
tup	-1.652	9.081e-06
Sox21b	-1.679	0.0006362
CG17803	-1.686	0.006033
CG6813	-1.695	0.0001019
rn	-1.716	1.149e-05
Lim3	-1.721	0.000264
ems	-1.728	0.002555
CG17801	-1.736	0.008434
toe	-1.788	5.502e-05
slp2	-1.802	0.000729
gl	-1.803	5.61e-05
opa	-1.821	0.003525
btd	-1.822	0.003055
CG13775	-1.825	0.0001454
CG14860	-1.896	0.002909
kn	-1.918	1.434e-05
byn	-1.982	0.0004888
D	-1.982	0.0001305
sv	-2.004	2.945e-10
gt	-2.031	0.0001503
acj6	-2.061	8.422e-06
CG7368	-2.07	0.0002081
salr	-2.078	1.279e-08
Dfd	-2.088	6.894e-05
ss	-2.137	9.78e-07
trh	-2.138	2.011e-13
CG4374	-2.145	3.363e-06
Scr	-2.155	4.091e-06
nau	-2.189	9.132e-06
CG18265	-2.196	2.474e-09
CG10348	-2.242	6.979e-07
zen	-2.293	0.002232
Fer1	-2.298	0.004616
en	-2.314	0.0009984
H2.0	-2.318	0.002352
pnr	-2.34	4.41e-07
sob	-2.347	0.000105
lov	-2.373	0.001431
Sox15	-2.391	1.113e-05
Awh	-2.403	0.001382
topi	-2.438	0.0003181
ara	-2.449	9.63e-06
B-H2	-2.47	9.041e-08
TfAP-2	-2.479	0.0001871
grn	-2.48	4.624e-07
B-H1	-2.48	0.0008523
CG32532	-2.518	2.102e-05
rib	-2.523	0.00603
Poxm	-2.533	1.402e-06
dpn	-2.534	0.001428
Pph13	-2.538	0.0002816
ey	-2.576	4.543e-07
sc	-2.578	0.008095
twi	-2.583	3.854e-05
Doc1	-2.592	5.899e-05
E5	-2.601	5.811e-06
hbn	-2.608	0.002512
CG32006	-2.679	7.239e-05
bap	-2.693	0.0002431
bab1	-2.701	1.577e-10
eyg	-2.714	1.538e-06
Vsx2	-2.718	0.0001488
Oli	-2.738	0.0005134
fd102C	-2.758	0.0005627
tap	-2.831	0.0003334
FoxP	-2.831	1.577e-10
CG42741	-2.832	0.000255
erm	-2.86	1.846e-07
bin	-2.892	6.683e-06
croc	-2.937	2.801e-05
lbl	-2.939	3.662e-06
unpg	-2.987	0.004162
HLH54F	-2.988	0.005604
CG13287	-3.054	0.001116
Optix	-3.062	1.716e-05
cas	-3.076	1.363e-10
danr	-3.116	4.303e-07
lbe	-3.123	0.0003163
lz	-3.154	3.081e-11
RunxA	-3.203	5.657e-08
run	-3.211	3.167e-05
bsh	-3.22	0.002765
slou	-3.222	0.004281
otp	-3.355	7.126e-11
CG11085	-3.355	0.002285
CG11294	-3.388	0.0001033
Ets96B	-3.397	6.011e-09
CG4328	-3.398	0.002893
eg	-3.402	7.955e-05
Oaz	-3.417	5.723e-05
fd59A	-3.46	0.001314
Ets65A	-3.475	9.709e-09
CG13617	-3.504	0.003781
CG13894	-3.545	1.457e-06
Hmx	-3.549	3.259e-08
Rx	-3.585	1.86e-05
pb	-3.619	1.042e-07
al	-3.658	4.271e-06
C15	-3.81	0.0003086
dan	-3.81	0.0001076
Doc3	-3.813	0.0007004
dimm	-3.869	0.0004282
eve	-3.871	5.203e-05
Dbx	-3.902	4.473e-05
hkb	-3.91	1.061e-05
Vsx1	-3.917	7.812e-07
CG34367	-3.945	0.000375
nerfin-1	-3.946	7.675e-05
E(spl)m7-HLH	-3.962	0.0002569
HGTX	-4.011	1.473e-09
CG7963	-4.012	0.0002494
lms	-4.045	1.349e-06
prd	-4.105	1.403e-07
sna	-4.141	0.002998
fd19B	-4.143	0.003655
dmrt99B	-4.17	2.29e-06
Gsc	-4.226	0.00374
RunxB	-4.242	5.402e-05
sisA	-4.243	0.009601
Poxn	-4.249	1.46e-09
PHDP	-4.262	0.002717
gsb	-4.355	0.000652
CG9876	-4.356	0.006096
wor	-4.367	1.755e-05
nerfin-2	-4.371	1.144e-07
ase	-4.427	3.188e-07
term	-4.46	0.004252
inv	-4.466	1.006e-07
HHEX	-4.475	4.21e-05
E(spl)mgamma-HLH	-4.51	0.001086
Neu2	-4.528	8.867e-05
E(spl)m8-HLH	-4.537	0.002061
CG18599	-4.631	0.0002061
Doc2	-4.659	0.0006841
HLH4C	-4.662	0.0005663
gcm	-4.739	0.00458
dsf	-4.771	4.529e-05
CG33557	-4.872	0.006958
lmd	-4.965	4.591e-10
CG7691	-4.973	0.000133
E(spl)m5-HLH	-4.976	0.006159
Hr51	-4.98	8.417e-08
gsb-n	-4.99	2.705e-07
CG4318	-5.132	8.379e-05
Kr	-5.151	2.654e-09
gcm2	-5.176	0.001807
HLH3B	-5.21	1.437e-05
Hey	-5.231	1.378e-06
tll	-5.26	7.865e-06
Hr83	-5.29	0.0007808
tin	-5.36	3.286e-06
fd96Cb	-5.511	5.402e-05
ftz	-5.6	9.431e-05
Fer2	-5.706	2.841e-05
OdsH	-5.938	1.055e-05
ro	-6.017	0.001023
CG15710	-6.048	0.0003508
dmrt93B	-6.117	2.365e-06
zen2	-6.297	0.001434
CG7786	-6.432	0.0001347
dmrt11E	-6.528	1.46e-06
CG34031	-6.586	8.336e-05
E(spl)mdelta-HLH	-6.624	1.951e-06
CG15696	-7.248	0.0005221
Fer3	-7.342	0.0005514
CG15336	-7.427	0.001094
cato	-7.578	0.0006299
fd3F	-7.829	2.746e-06
fd96Ca	-8.983	2.222e-08

9.1.4 Venn Diagram

9.2 GWAS

9.2.1 CTmax

gene	grps	AvgMixedPval
CG42741	INTRON	3.06e-05
disco-r	INTRON	1.70e-05
HmgD	INTRON	8.63e-05
HmgZ	DOWNSTREAM	7.74e-05
lola	INTRON	1.88e-05
Oaz	INTRON	8.31e-05
Sp1	INTRON	7.15e-05
svp	INTRON	5.22e-05
twi	INTRON	3.06e-05

9.2.2 CTmin

gene	grps	AvgMixedPval
bs	INTRON	2.14e-05
CHES-1-like	INTRON	6.66e-05
dar1	INTRON	2.88e-05
EcR	INTRON	3.60e-05
Eip75B	INTRON	8.11e-05
erm	INTRON	2.87e-05
fru	INTRON	8.46e-05
Glut4EF	INTRON	6.72e-05
ham	INTRON	1.49e-05
Rx	DOWNSTREAM	8.57e-05
Sp1	INTRON	2.43e-05
sr	INTRON	4.73e-05

9.2.3 Venn diagram